Low-dose remifentanil increases regional cerebral blood flow and regional cerebral blood volume, but decreases regional mean transit time and regional cerebrovascular resistance in volunteers

We have used contrast media-enhanced perfusion magnetic resonance imaging MRI to measure regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV), regional mean transit time (rMTT) and regional cerebrovascular resistance (rCVR) in volunteers at baseline and during infusion of remif...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2000-08, Vol.85 (2), p.199-204
Hauptverfasser:	Lorenz, I.H., Kolbitsch, C., Schocke, M., Kremser, C., Zschiegner, F., Hinteregger, M., Felber, S., Hörmann, C., Benzer, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analgesics analgesics opioid, remifentanil Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacology Biological and medical sciences Blood Flow Velocity - drug effects Blood Volume - drug effects blood, volume Brain - blood supply Brain - drug effects brain, blood flow brain, cortex, cerebral Cerebrovascular Circulation - drug effects Contrast Media Humans Hypnotics and Sedatives - administration & dosage Hypnotics and Sedatives - pharmacology Magnetic Resonance Imaging Male measurement techniques, nuclear magnetic resonance Medical sciences Neural Inhibition - drug effects Neuropharmacology Pharmacology. Drug treatments Piperidines - administration & dosage Piperidines - pharmacology Remifentanil Time Factors Vascular Resistance - drug effects
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