Relationship between symptoms and objective measures of airway obstruction in asthmatic patients
The objective of this study was to determine the relationship between asthma symptoms and the degree of airway obstruction as measured by the forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) in a group of 64 asthmatic patients with clinically stable disease attendin...
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Veröffentlicht in: | Asian Pacific journal of allergy and immunology 2001-06, Vol.19 (2), p.79-83 |
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creator | Liam, C K Goh, C T Isahak, M Lim, K H Wong, C M |
description | The objective of this study was to determine the relationship between asthma symptoms and the degree of airway obstruction as measured by the forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) in a group of 64 asthmatic patients with clinically stable disease attending a university-based urban asthma clinic. Asthma symptoms did not correlate with the degree of airway obstruction as measured by prebronchodilator PEFR (total asthma symptom score vs PEFR: r = -0.214, p = 0.104, n = 59) and only correlated poorly with prebronchodilator FEV1 (total asthma symptom score vs FEV1: r = -0.256, p = 0.041, n = 64). These results lend support to the recommendation that airway obstruction should be measured objectively when assessing patients with chronic persistent asthma. |
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Asthma symptoms did not correlate with the degree of airway obstruction as measured by prebronchodilator PEFR (total asthma symptom score vs PEFR: r = -0.214, p = 0.104, n = 59) and only correlated poorly with prebronchodilator FEV1 (total asthma symptom score vs FEV1: r = -0.256, p = 0.041, n = 64). These results lend support to the recommendation that airway obstruction should be measured objectively when assessing patients with chronic persistent asthma.</description><identifier>ISSN: 0125-877X</identifier><identifier>PMID: 11699724</identifier><language>eng</language><publisher>Thailand: The Allergy and Immunology Society</publisher><subject>Administration, Inhalation ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Airway Obstruction - complications ; Airway Obstruction - diagnosis ; Asthma - complications ; Asthma - epidemiology ; Asthma - physiopathology ; Bronchodilator Agents - therapeutic use ; Female ; Forced Expiratory Volume - drug effects ; Forced Expiratory Volume - physiology ; Humans ; Malaysia - epidemiology ; Male ; Middle Aged ; Peak Expiratory Flow Rate - drug effects ; Peak Expiratory Flow Rate - physiology ; Predictive Value of Tests ; Severity of Illness Index ; Spirometry ; Surveys and Questionnaires</subject><ispartof>Asian Pacific journal of allergy and immunology, 2001-06, Vol.19 (2), p.79-83</ispartof><rights>Copyright The Allergy and Immunology Society of Thailand Jun 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11699724$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liam, C K</creatorcontrib><creatorcontrib>Goh, C T</creatorcontrib><creatorcontrib>Isahak, M</creatorcontrib><creatorcontrib>Lim, K H</creatorcontrib><creatorcontrib>Wong, C M</creatorcontrib><title>Relationship between symptoms and objective measures of airway obstruction in asthmatic patients</title><title>Asian Pacific journal of allergy and immunology</title><addtitle>Asian Pac J Allergy Immunol</addtitle><description>The objective of this study was to determine the relationship between asthma symptoms and the degree of airway obstruction as measured by the forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) in a group of 64 asthmatic patients with clinically stable disease attending a university-based urban asthma clinic. Asthma symptoms did not correlate with the degree of airway obstruction as measured by prebronchodilator PEFR (total asthma symptom score vs PEFR: r = -0.214, p = 0.104, n = 59) and only correlated poorly with prebronchodilator FEV1 (total asthma symptom score vs FEV1: r = -0.256, p = 0.041, n = 64). These results lend support to the recommendation that airway obstruction should be measured objectively when assessing patients with chronic persistent asthma.</description><subject>Administration, Inhalation</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Airway Obstruction - complications</subject><subject>Airway Obstruction - diagnosis</subject><subject>Asthma - complications</subject><subject>Asthma - epidemiology</subject><subject>Asthma - physiopathology</subject><subject>Bronchodilator Agents - therapeutic use</subject><subject>Female</subject><subject>Forced Expiratory Volume - drug effects</subject><subject>Forced Expiratory Volume - physiology</subject><subject>Humans</subject><subject>Malaysia - epidemiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Peak Expiratory Flow Rate - drug effects</subject><subject>Peak Expiratory Flow Rate - physiology</subject><subject>Predictive Value of Tests</subject><subject>Severity of Illness Index</subject><subject>Spirometry</subject><subject>Surveys and Questionnaires</subject><issn>0125-877X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkE1LxDAQhntQ3EX3L0hA8FZImjZpjrL4BQuCKHir6XTCZmmTmqQu--_t4npxDvMe5uHhZc6yJWVFlddSfiyyVYw7Oo9grK7Ki2zBmFBKFuUy-3zFXifrXdzakbSY9oiOxMMwJj9Eol1HfLtDSPYbyYA6TgEj8YZoG_b6MB9jChMcDcQ6omPaDrMPyDhvdCleZedG9xFXp7zM3h_u39ZP-ebl8Xl9t8nHglcpFwJ0oblRIErGOOcddFKWYCoFRjHgsjKtNEwgSAqG0a4GpXmngBfABfLL7PbXOwb_NWFMzWAjYN9rh36KjSwKUZaUzuDNP3Dnp-Dmbg2jnKq6kvJIXZ-oqR2wa8ZgBx0Ozd_n-A8Pp2vY</recordid><startdate>20010601</startdate><enddate>20010601</enddate><creator>Liam, C K</creator><creator>Goh, C T</creator><creator>Isahak, M</creator><creator>Lim, K H</creator><creator>Wong, C M</creator><general>The Allergy and Immunology Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BVBZV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20010601</creationdate><title>Relationship between symptoms and objective measures of airway obstruction in asthmatic patients</title><author>Liam, C K ; Goh, C T ; Isahak, M ; Lim, K H ; Wong, C M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p235t-66ca2a3f9c6411333dcd774cf59cf91c375fb7f16ec70cf10d8c9a3d9c32c36e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Administration, Inhalation</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Airway Obstruction - complications</topic><topic>Airway Obstruction - diagnosis</topic><topic>Asthma - complications</topic><topic>Asthma - epidemiology</topic><topic>Asthma - physiopathology</topic><topic>Bronchodilator Agents - therapeutic use</topic><topic>Female</topic><topic>Forced Expiratory Volume - drug effects</topic><topic>Forced Expiratory Volume - physiology</topic><topic>Humans</topic><topic>Malaysia - epidemiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Peak Expiratory Flow Rate - drug effects</topic><topic>Peak Expiratory Flow Rate - physiology</topic><topic>Predictive Value of Tests</topic><topic>Severity of Illness Index</topic><topic>Spirometry</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liam, C K</creatorcontrib><creatorcontrib>Goh, C T</creatorcontrib><creatorcontrib>Isahak, M</creatorcontrib><creatorcontrib>Lim, K H</creatorcontrib><creatorcontrib>Wong, C M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>East & South Asia Database</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Asian Pacific journal of allergy and immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liam, C K</au><au>Goh, C T</au><au>Isahak, M</au><au>Lim, K H</au><au>Wong, C M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship between symptoms and objective measures of airway obstruction in asthmatic patients</atitle><jtitle>Asian Pacific journal of allergy and immunology</jtitle><addtitle>Asian Pac J Allergy Immunol</addtitle><date>2001-06-01</date><risdate>2001</risdate><volume>19</volume><issue>2</issue><spage>79</spage><epage>83</epage><pages>79-83</pages><issn>0125-877X</issn><abstract>The objective of this study was to determine the relationship between asthma symptoms and the degree of airway obstruction as measured by the forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) in a group of 64 asthmatic patients with clinically stable disease attending a university-based urban asthma clinic. Asthma symptoms did not correlate with the degree of airway obstruction as measured by prebronchodilator PEFR (total asthma symptom score vs PEFR: r = -0.214, p = 0.104, n = 59) and only correlated poorly with prebronchodilator FEV1 (total asthma symptom score vs FEV1: r = -0.256, p = 0.041, n = 64). These results lend support to the recommendation that airway obstruction should be measured objectively when assessing patients with chronic persistent asthma.</abstract><cop>Thailand</cop><pub>The Allergy and Immunology Society</pub><pmid>11699724</pmid><tpages>5</tpages></addata></record> |
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subjects | Administration, Inhalation Adolescent Adult Aged Aged, 80 and over Airway Obstruction - complications Airway Obstruction - diagnosis Asthma - complications Asthma - epidemiology Asthma - physiopathology Bronchodilator Agents - therapeutic use Female Forced Expiratory Volume - drug effects Forced Expiratory Volume - physiology Humans Malaysia - epidemiology Male Middle Aged Peak Expiratory Flow Rate - drug effects Peak Expiratory Flow Rate - physiology Predictive Value of Tests Severity of Illness Index Spirometry Surveys and Questionnaires |
title | Relationship between symptoms and objective measures of airway obstruction in asthmatic patients |
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