Relationship between symptoms and objective measures of airway obstruction in asthmatic patients

The objective of this study was to determine the relationship between asthma symptoms and the degree of airway obstruction as measured by the forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) in a group of 64 asthmatic patients with clinically stable disease attendin...

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Veröffentlicht in:Asian Pacific journal of allergy and immunology 2001-06, Vol.19 (2), p.79-83
Hauptverfasser: Liam, C K, Goh, C T, Isahak, M, Lim, K H, Wong, C M
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container_title Asian Pacific journal of allergy and immunology
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creator Liam, C K
Goh, C T
Isahak, M
Lim, K H
Wong, C M
description The objective of this study was to determine the relationship between asthma symptoms and the degree of airway obstruction as measured by the forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) in a group of 64 asthmatic patients with clinically stable disease attending a university-based urban asthma clinic. Asthma symptoms did not correlate with the degree of airway obstruction as measured by prebronchodilator PEFR (total asthma symptom score vs PEFR: r = -0.214, p = 0.104, n = 59) and only correlated poorly with prebronchodilator FEV1 (total asthma symptom score vs FEV1: r = -0.256, p = 0.041, n = 64). These results lend support to the recommendation that airway obstruction should be measured objectively when assessing patients with chronic persistent asthma.
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Asthma symptoms did not correlate with the degree of airway obstruction as measured by prebronchodilator PEFR (total asthma symptom score vs PEFR: r = -0.214, p = 0.104, n = 59) and only correlated poorly with prebronchodilator FEV1 (total asthma symptom score vs FEV1: r = -0.256, p = 0.041, n = 64). 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source MEDLINE; Alma/SFX Local Collection
subjects Administration, Inhalation
Adolescent
Adult
Aged
Aged, 80 and over
Airway Obstruction - complications
Airway Obstruction - diagnosis
Asthma - complications
Asthma - epidemiology
Asthma - physiopathology
Bronchodilator Agents - therapeutic use
Female
Forced Expiratory Volume - drug effects
Forced Expiratory Volume - physiology
Humans
Malaysia - epidemiology
Male
Middle Aged
Peak Expiratory Flow Rate - drug effects
Peak Expiratory Flow Rate - physiology
Predictive Value of Tests
Severity of Illness Index
Spirometry
Surveys and Questionnaires
title Relationship between symptoms and objective measures of airway obstruction in asthmatic patients
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