Age-related Alteration of Gap Junction Distribution and Connexin Expression in Rat Aortic Endothelium

We investigated endothelial gap junctions and their three component connexins, connexin37 (Cx37), Cx40, and Cx43, during growth and senescence in rat aorta by en face immunoconfocal microscopy and electron microscopy. Gap junction spots labeled by specific antisera against Cx37, Cx40, and Cx43 were...

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Veröffentlicht in:	The journal of histochemistry and cytochemistry 2000-10, Vol.48 (10), p.1377-1389
Hauptverfasser:	Yeh, Hung-I, Chang, Hao-Min, Lu, Wen-Wei, Lee, Yi-Nan, Ko, Yu-Shien, Severs, Nicholas J, Tsai, Cheng-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Animals, Newborn Aorta - cytology Aorta - metabolism Aorta - ultrastructure Blotting, Western Connexins - immunology Connexins - metabolism Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Endothelium, Vascular - ultrastructure Fluorescent Antibody Technique Gap Junctions - metabolism Immune Sera Microscopy, Confocal Microscopy, Electron Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
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