Differential antigenicity of recombinant polyepitope-antigens based on loop- and helix-forming B and T cell epitopes

To investigate a strategy for the design of chimeric antigens based on B cell epitopes (BCEs) we have genetically recombined multiple copies of loop- (L) and helix-forming (H) sequential and protective BCEs of the measles virus hemagglutinin protein (MVH) in a number of high-molecular-weight polyepi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of immunological methods 2000-08, Vol.242 (1), p.145-157
Hauptverfasser:	Theisen, D.M, Bouche, F.B, El Kasmi, K.C, von der Ahe, I, Ammerlaan, W, Demotz, S, Muller, C.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antigens, Viral - biosynthesis Antigens, Viral - chemistry Antigens, Viral - genetics Antigens, Viral - immunology Biological and medical sciences Cell Line Cricetinae Epitopes, B-Lymphocyte - biosynthesis Epitopes, B-Lymphocyte - chemistry Epitopes, B-Lymphocyte - genetics Epitopes, B-Lymphocyte - immunology Epitopes, T-Lymphocyte - biosynthesis Epitopes, T-Lymphocyte - chemistry Epitopes, T-Lymphocyte - genetics Epitopes, T-Lymphocyte - immunology Fundamental and applied biological sciences. Psychology Gene Expression hemagglutinins Hemagglutinins, Viral - biosynthesis Hemagglutinins, Viral - chemistry Hemagglutinins, Viral - genetics Hemagglutinins, Viral - immunology Measles virus Microbiology Miscellaneous Molecular Sequence Data Peptides - chemistry Peptides - genetics Peptides - immunology Protein Conformation Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology Recombinant polyepitopes Sequential B cell epitopes tt830–844, Hemagglutinin protein Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!