EFFECT OF AGING ON UNSCHEDULED DNA SYNTHESIS INDUCTION BY UV-B IRRADIATION IN HAIRLESS MOUSE EPIDERMIS

Age-related induction of unscheduled DNA synthesis(UDS)by ultraviolet B(UV-B)irradiation was investigated in the epidermis of female hairless mice by means of an in vivo-in vitro assay using a liquid scintillation counting method. Skin samples were taken and cultured in a medium containing[3H]thymid...

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Veröffentlicht in:	Journal of toxicological sciences 2000/08/17, Vol.25(3), pp.181-188
Hauptverfasser:	MORI, Masaki, KOBAYASHI, Hiroshi, SUGIYAMA, Chiyomi, KATSUMURA, Yoshio, FURIHATA, Chie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - metabolism Animals Biological and medical sciences Biological effects of radiation DNA - biosynthesis DNA Repair - radiation effects Epidermis - metabolism Epidermis - radiation effects Female Fundamental and applied biological sciences. Psychology Mice Mice, Hairless Non ionizing radiations. Hertzian waves. Biooptics Thymidine - metabolism Tissues, organs and organisms biophysics Ultraviolet Rays
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