Elevated K + induces myristoylated alanine-rich C-kinase substrate phosphorylation and phospholipase D activation in glomerulosa cells

Elevated extracellular potassium concentrations ([K +] e) are known to stimulate aldosterone secretion from adrenal glomerulosa cells in vivo and in vitro. The mechanism is thought to involve depolarization-elicited activation of voltage-dependent calcium channels and an increase in calcium influx....

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Veröffentlicht in:Molecular and cellular endocrinology 2001-11, Vol.184 (1), p.65-76
Hauptverfasser: Betancourt-Calle, Soraya, Jung, EunMi, White, Stephanie, Ray, Sagarika, Zheng, Xiangjian, Calle, Roberto A, Bollag, Wendy B
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Sprache:eng
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