Training-induced changes of motor cortex representations in stroke patients
Objective– To study changes in motor cortex representations after a single session of physiotherapy in stroke patients. Methods– TMS mapping was used to evaluate the motor output map of the abductor pollicis brevis (APB) in both hemispheres. Stroke patients (4–8 weeks after the infarction) were stud...
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| Veröffentlicht in: | Acta neurologica Scandinavica 2000-05, Vol.101 (5), p.321-326 |
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| container_title | Acta neurologica Scandinavica |
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| creator | Liepert, J. Graef, S. Uhde, I. Leidner, O. Weiller, C. |
| description | Objective– To study changes in motor cortex representations after a single session of physiotherapy in stroke patients. Methods– TMS mapping was used to evaluate the motor output map of the abductor pollicis brevis (APB) in both hemispheres. Stroke patients (4–8 weeks after the infarction) were studied prior to a training session aimed at improving dexterity and 1 h and 1 day after the training. Results– Prior to the training, the APB representation area in the affected hemisphere was significantly smaller than on the non‐affected side. After therapy, the cortical motor output to the paretic APB was significantly enlarged, and motor function was improved. One day later, these effects were partially reversed. Motor thresholds remained significantly increased in the affected hemisphere before and after the therapy. Conclusion– A single session of physiotherapy produces a use‐dependent enlargement of motor cortex representations paralleled by an improvement of motor function in stroke patients. |
| doi_str_mv | 10.1034/j.1600-0404.2000.90337a.x |
| format | Article |
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Methods– TMS mapping was used to evaluate the motor output map of the abductor pollicis brevis (APB) in both hemispheres. Stroke patients (4–8 weeks after the infarction) were studied prior to a training session aimed at improving dexterity and 1 h and 1 day after the training. Results– Prior to the training, the APB representation area in the affected hemisphere was significantly smaller than on the non‐affected side. After therapy, the cortical motor output to the paretic APB was significantly enlarged, and motor function was improved. One day later, these effects were partially reversed. Motor thresholds remained significantly increased in the affected hemisphere before and after the therapy. Conclusion– A single session of physiotherapy produces a use‐dependent enlargement of motor cortex representations paralleled by an improvement of motor function in stroke patients.</description><identifier>ISSN: 0001-6314</identifier><identifier>EISSN: 1600-0404</identifier><identifier>DOI: 10.1034/j.1600-0404.2000.90337a.x</identifier><identifier>PMID: 10987321</identifier><identifier>CODEN: ANRSAS</identifier><language>eng</language><publisher>Copenhagen: Munksgaard International Publishers</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Diseases of the nervous system ; Evoked Potentials, Motor - physiology ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Motor Cortex - physiology ; Physical Therapy Modalities ; physiotherapy ; plasticity ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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Methods– TMS mapping was used to evaluate the motor output map of the abductor pollicis brevis (APB) in both hemispheres. Stroke patients (4–8 weeks after the infarction) were studied prior to a training session aimed at improving dexterity and 1 h and 1 day after the training. Results– Prior to the training, the APB representation area in the affected hemisphere was significantly smaller than on the non‐affected side. After therapy, the cortical motor output to the paretic APB was significantly enlarged, and motor function was improved. One day later, these effects were partially reversed. Motor thresholds remained significantly increased in the affected hemisphere before and after the therapy. Conclusion– A single session of physiotherapy produces a use‐dependent enlargement of motor cortex representations paralleled by an improvement of motor function in stroke patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Diseases of the nervous system</subject><subject>Evoked Potentials, Motor - physiology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Motor Cortex - physiology</subject><subject>Physical Therapy Modalities</subject><subject>physiotherapy</subject><subject>plasticity</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>stroke</subject><subject>Stroke Rehabilitation</subject><subject>transcranial magnetic stimulation</subject><subject>Treatment Outcome</subject><issn>0001-6314</issn><issn>1600-0404</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkctu2zAQRYmiQeMk_YVCBYrupJAiJdK7GoadFnkuHGRJjKhRSlumXFJGnL8vVTtuVvM6uMDcS8hXRjNGubhcZqykNKWCiiynlGZjyrmEbPeBjI6Xj2QUTywtOROn5CyEZZxyKcQncsroWEmesxG5Xniwzrrn1Lp6a7BOzG9wzxiSrknWXd_5xHS-x13iceMxoOuht50LiXVJ6H23wmQTN3EfLshJA23Az4d6Th7ns8X0Z3pzf_VrOrlJTUHFJK2koZWqOdZVXVdKMAUNyJxXkgEXORaijmWsEKiERimjCikpB14WqApo-Dn5vtfd-O7PFkOv1zYYbFtw2G2DlnlelCVjEfxyALfVGmu98XYN_lW_vR-BbwcAgoG28eCMDf85XkTDBuzHHnuxLb6-k9FDHHqpB9P1YLoe4tD7OPROT-5m__pJlEj3EjZEM48S4Fe6lFwW-unuSt9es8XDXE31mP8FIMaNzA</recordid><startdate>200005</startdate><enddate>200005</enddate><creator>Liepert, J.</creator><creator>Graef, S.</creator><creator>Uhde, I.</creator><creator>Leidner, O.</creator><creator>Weiller, C.</creator><general>Munksgaard International Publishers</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200005</creationdate><title>Training-induced changes of motor cortex representations in stroke patients</title><author>Liepert, J. ; Graef, S. ; Uhde, I. ; Leidner, O. ; Weiller, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504A-b7c0b8d3edbddb8418afa723b71a342e54d34298ea07af88c857703a365e85af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Diseases of the nervous system</topic><topic>Evoked Potentials, Motor - physiology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Motor Cortex - physiology</topic><topic>Physical Therapy Modalities</topic><topic>physiotherapy</topic><topic>plasticity</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>stroke</topic><topic>Stroke Rehabilitation</topic><topic>transcranial magnetic stimulation</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liepert, J.</creatorcontrib><creatorcontrib>Graef, S.</creatorcontrib><creatorcontrib>Uhde, I.</creatorcontrib><creatorcontrib>Leidner, O.</creatorcontrib><creatorcontrib>Weiller, C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta neurologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liepert, J.</au><au>Graef, S.</au><au>Uhde, I.</au><au>Leidner, O.</au><au>Weiller, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Training-induced changes of motor cortex representations in stroke patients</atitle><jtitle>Acta neurologica Scandinavica</jtitle><addtitle>Acta Neurol Scand</addtitle><date>2000-05</date><risdate>2000</risdate><volume>101</volume><issue>5</issue><spage>321</spage><epage>326</epage><pages>321-326</pages><issn>0001-6314</issn><eissn>1600-0404</eissn><coden>ANRSAS</coden><abstract>Objective– To study changes in motor cortex representations after a single session of physiotherapy in stroke patients. Methods– TMS mapping was used to evaluate the motor output map of the abductor pollicis brevis (APB) in both hemispheres. Stroke patients (4–8 weeks after the infarction) were studied prior to a training session aimed at improving dexterity and 1 h and 1 day after the training. Results– Prior to the training, the APB representation area in the affected hemisphere was significantly smaller than on the non‐affected side. After therapy, the cortical motor output to the paretic APB was significantly enlarged, and motor function was improved. One day later, these effects were partially reversed. Motor thresholds remained significantly increased in the affected hemisphere before and after the therapy. Conclusion– A single session of physiotherapy produces a use‐dependent enlargement of motor cortex representations paralleled by an improvement of motor function in stroke patients.</abstract><cop>Copenhagen</cop><pub>Munksgaard International Publishers</pub><pmid>10987321</pmid><doi>10.1034/j.1600-0404.2000.90337a.x</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Biological and medical sciences Diseases of the nervous system Evoked Potentials, Motor - physiology Female Humans Male Medical sciences Middle Aged Motor Cortex - physiology Physical Therapy Modalities physiotherapy plasticity Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) stroke Stroke Rehabilitation transcranial magnetic stimulation Treatment Outcome |
| title | Training-induced changes of motor cortex representations in stroke patients |
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