Double-stranded RNA-induced interferon regulatory factor-1 gene expression in FRTL-5 rat thyroid cells

Double-stranded RNA (dsRNA) plays a role in the regulation of cell growth and apoptosis as well as in the cellular antiviral responses. However, it remains unknown if dsRNA-activated signaling systems are functional in the thyroid. Here we report the presence of the dsRNA-dependent protein kinase (P...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular and cellular endocrinology 2001-11, Vol.184 (1), p.77-86
Hauptverfasser:	Mori, Kouki, Yoshida, Katsumi, Tani, Jun-ichi, Nakagawa, Yoshinori, Hoshikawa, Saeko, Ito, Sadayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line DNA-Binding Proteins - drug effects DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Double-stranded RNA eIF-2 Kinase - analysis eIF-2 Kinase - physiology Gene Expression Regulation - drug effects Interferon Regulatory Factor-1 Interferon Type I - drug effects Interferon Type I - genetics IRF-1 protein NF-kappa B - metabolism Phosphoproteins - drug effects Phosphoproteins - genetics Poly I-C - pharmacology Protein Binding - drug effects Rats RNA, Double-Stranded - pharmacology RNA, Messenger - drug effects RNA, Messenger - metabolism Signal transduction Signal Transduction - drug effects Signal Transduction - physiology Stat1 protein STAT1 Transcription Factor Thyroid Thyroid Gland - cytology Thyroid Gland - metabolism Trans-Activators - drug effects Trans-Activators - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!