Relationship between transcardiac extraction of aldosterone and left ventricular remodeling in patients with first acute myocardial infarction: extracting aldosterone through the heart promotes ventricular remodeling after acute myocardial infarction

OBJECTIVES The purpose of this study was to evaluate whether plasma aldosterone (ALD) is extracted or produced through the heart in patients with acute myocardial infarction (AMI) and to determine the relationship between transcardiac extraction of plasma ALD and left ventricular (LV) remodeling. BA...

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Veröffentlicht in:	Journal of the American College of Cardiology 2001-11, Vol.38 (5), p.1375-1382
Hauptverfasser:	Hayashi, Masaru, Tsutamoto, Takayoshi, Wada, Atsuyuki, Maeda, Keiko, Mabuchi, Naoko, Tsutsui, Takashi, Matsui, Toshiki, Fujii, Masanori, Matsumoto, Takehiro, Yamamoto, Takashi, Horie, Hajime, Ohnishi, Masato, Kinoshita, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Aged Aldosterone - blood Aldosterone - physiology Angioplasty, Balloon, Coronary Angiotensin-Converting Enzyme Inhibitors - therapeutic use Aorta - chemistry Biological and medical sciences Biomarkers - analysis Biomarkers - blood Cardiology. Vascular system Coronary heart disease Coronary Vessels - chemistry Cytochrome P-450 CYP11B2 - analysis Cytochrome P-450 CYP11B2 - physiology Disease Progression Enalapril - therapeutic use Female Fibrosis Heart Heart Failure - etiology Heart Failure - metabolism Heart Failure - pathology Heart Failure - physiopathology Heart Failure - therapy Humans Male Medical sciences Middle Aged Mineralocorticoid Receptor Antagonists Multivariate Analysis Myocardial Infarction - complications Myocardial Infarction - metabolism Myocardial Infarction - pathology Myocardial Infarction - physiopathology Myocardial Infarction - therapy Peptide Fragments - blood Procollagen - blood Prospective Studies Severity of Illness Index Stroke Volume Time Factors Veins Ventricular Remodeling - physiology
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