Variance component linkage analysis indicates a QTL for femoral neck bone mineral density on chromosome 1p36

Osteoporosis is a common condition characterized by reduced skeletal strength and increased susceptibility to fracture. Eight million Americans over the age of 50 have osteoporosis of the femoral neck. The most important risk factor for osteoporosis is low bone mineral density (BMD), and several epi...

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Veröffentlicht in:	Human molecular genetics 2001-10, Vol.10 (21), p.2447-2452
Hauptverfasser:	DEVOTO, Marcella, SPECCHIA, Claudia, LI, Hui-Hua, CAMINIS, John, TENENHOUSE, Alan, RODRIGUEZ, Hetty, SPOTILA, Loretta D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Analysis of Variance Biological and medical sciences Body Height Body Mass Index Body Weight Bone Density - genetics chromosome 1 Chromosome Mapping Chromosomes, Human, Pair 1 - genetics Diseases of the osteoarticular system DNA - genetics Family Health Female Femur Neck - metabolism Genetic Linkage Genotype Humans Lod Score Male Medical sciences Microsatellite Repeats Middle Aged Osteoporosis. Osteomalacia. Paget disease Quantitative Trait, Heritable Software
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