Evidence for multidrug resistance-1 P-glycoprotein-dependent regulation of cellular ATP permeability

The mechanisms responsible for regulating epithelial ATP permeability and purinergic signaling are not well defined. Based on the observations that members of the ATP-binding cassette (ABC)1 family of proteins may contribute to ATP release, the purpose of these studies was to assess whether multidru...

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Veröffentlicht in:	The Journal of membrane biology 2001-10, Vol.183 (3), p.165-173
Hauptverfasser:	Roman, R M, Lomri, N, Braunstein, G, Feranchak, A P, Simeoni, L A, Davison, A K, Mechetner, E, Schwiebert, E M, Fitz, J G
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells - cytology Adenosine Triphosphate - antagonists & inhibitors Adenosine Triphosphate - metabolism Animals Antibodies - immunology Antibodies - pharmacology ATP Binding Cassette Transporter, Subfamily B - metabolism ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors ATP Binding Cassette Transporter, Subfamily B, Member 1 - immunology ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism ATP-Binding Cassette Sub-Family B Member 4 Carcinoma, Hepatocellular - metabolism Cell Membrane Permeability - drug effects Cell Membrane Permeability - physiology Cell Size - drug effects Cells, Cultured - cytology Chlorides - metabolism Cyclosporine - pharmacology Humans Mice Rats Tumor Cells, Cultured - cytology Tumor Cells, Cultured - metabolism Verapamil - pharmacology
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