Aging, habitual exercise, and dynamic arterial compliance
A reduction in compliance of the large-sized cardiothoracic (central) arteries is an independent risk factor for the development of cardiovascular disease with advancing age. We determined the role of habitual exercise on the age-related decrease in central arterial compliance by using both cross-se...
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| Veröffentlicht in: | Circulation (New York, N.Y.) N.Y.), 2000-09, Vol.102 (11), p.1270-1275 |
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| container_title | Circulation (New York, N.Y.) |
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| creator | TANAKA, Hirofumi DINENNO, Frank A MONAHAN, Kevin D CLEVENGER, Christopher M DESOUZA, Christopher A SEALS, Douglas R |
| description | A reduction in compliance of the large-sized cardiothoracic (central) arteries is an independent risk factor for the development of cardiovascular disease with advancing age.
We determined the role of habitual exercise on the age-related decrease in central arterial compliance by using both cross-sectional and interventional approaches. First, we studied 151 healthy men aged 18 to 77 years: 54 were sedentary, 45 were recreationally active, and 53 were endurance exercise-trained. Central arterial compliance (simultaneous B-mode ultrasound and arterial applanation tonometry on the common carotid artery) was lower (P: |
| doi_str_mv | 10.1161/01.cir.102.11.1270 |
| format | Article |
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We determined the role of habitual exercise on the age-related decrease in central arterial compliance by using both cross-sectional and interventional approaches. First, we studied 151 healthy men aged 18 to 77 years: 54 were sedentary, 45 were recreationally active, and 53 were endurance exercise-trained. Central arterial compliance (simultaneous B-mode ultrasound and arterial applanation tonometry on the common carotid artery) was lower (P:<0.05) in middle-aged and older men than in young men in all 3 groups. There were no significant differences between sedentary and recreationally active men at any age. However, arterial compliance in the endurance-trained middle-aged and older men was 20% to 35% higher than in the 2 less active groups (P:<0.01). As such, age-related differences in central arterial compliance were smaller in the endurance-trained men than in the sedentary and recreationally active men. Second, we studied 20 middle-aged and older (53+/-2 years) sedentary healthy men before and after a 3-month aerobic exercise intervention (primarily walking). Regular exercise increased central arterial compliance (P:<0.01) to levels similar to those of the middle-aged and older endurance-trained men. These effects were independent of changes in body mass, adiposity, arterial blood pressure, or maximal oxygen consumption.
Regular aerobic-endurance exercise attenuates age-related reductions in central arterial compliance and restores levels in previously sedentary healthy middle-aged and older men. This may be one mechanism by which habitual exercise lowers the risk of cardiovascular disease in this population.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/01.cir.102.11.1270</identifier><identifier>PMID: 10982542</identifier><identifier>CODEN: CIRCAZ</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adolescent ; Adult ; Aged ; Aging - physiology ; Arteries - physiology ; Biological and medical sciences ; Cardiology. Vascular system ; Coronary heart disease ; Cross-Sectional Studies ; Elasticity ; Exercise ; Heart ; Humans ; Life Style ; Male ; Medical sciences ; Middle Aged ; Physical Endurance ; Risk Factors ; Thoracic Arteries - physiology</subject><ispartof>Circulation (New York, N.Y.), 2000-09, Vol.102 (11), p.1270-1275</ispartof><rights>2000 INIST-CNRS</rights><rights>Copyright American Heart Association, Inc. Sep 12, 2000</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c557t-966e9bd7a6227772531c4424249f5d9f7fea44241438e9d33c599d024674370b3</citedby><cites>FETCH-LOGICAL-c557t-966e9bd7a6227772531c4424249f5d9f7fea44241438e9d33c599d024674370b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1486651$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10982542$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>TANAKA, Hirofumi</creatorcontrib><creatorcontrib>DINENNO, Frank A</creatorcontrib><creatorcontrib>MONAHAN, Kevin D</creatorcontrib><creatorcontrib>CLEVENGER, Christopher M</creatorcontrib><creatorcontrib>DESOUZA, Christopher A</creatorcontrib><creatorcontrib>SEALS, Douglas R</creatorcontrib><title>Aging, habitual exercise, and dynamic arterial compliance</title><title>Circulation (New York, N.Y.)</title><addtitle>Circulation</addtitle><description>A reduction in compliance of the large-sized cardiothoracic (central) arteries is an independent risk factor for the development of cardiovascular disease with advancing age.
We determined the role of habitual exercise on the age-related decrease in central arterial compliance by using both cross-sectional and interventional approaches. First, we studied 151 healthy men aged 18 to 77 years: 54 were sedentary, 45 were recreationally active, and 53 were endurance exercise-trained. Central arterial compliance (simultaneous B-mode ultrasound and arterial applanation tonometry on the common carotid artery) was lower (P:<0.05) in middle-aged and older men than in young men in all 3 groups. There were no significant differences between sedentary and recreationally active men at any age. However, arterial compliance in the endurance-trained middle-aged and older men was 20% to 35% higher than in the 2 less active groups (P:<0.01). As such, age-related differences in central arterial compliance were smaller in the endurance-trained men than in the sedentary and recreationally active men. Second, we studied 20 middle-aged and older (53+/-2 years) sedentary healthy men before and after a 3-month aerobic exercise intervention (primarily walking). Regular exercise increased central arterial compliance (P:<0.01) to levels similar to those of the middle-aged and older endurance-trained men. These effects were independent of changes in body mass, adiposity, arterial blood pressure, or maximal oxygen consumption.
Regular aerobic-endurance exercise attenuates age-related reductions in central arterial compliance and restores levels in previously sedentary healthy middle-aged and older men. This may be one mechanism by which habitual exercise lowers the risk of cardiovascular disease in this population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aging - physiology</subject><subject>Arteries - physiology</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary heart disease</subject><subject>Cross-Sectional Studies</subject><subject>Elasticity</subject><subject>Exercise</subject><subject>Heart</subject><subject>Humans</subject><subject>Life Style</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Physical Endurance</subject><subject>Risk Factors</subject><subject>Thoracic Arteries - physiology</subject><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkMtKAzEUhoMotlZfwIUMIq46Y3Jya5aleCkUBNF1SDOZmjKXmnTAvr0pLShyFoePfOcn_AhdE1wQIsgDJoX1oSAYEhcEJD5BQ8KB5YxTdYqGGGOVSwowQBcxrhMKKvk5GhCsJsAZDJGarny7GmefZum3vakz9-2C9dGNM9OWWblrTeNtZsLWBZ-ebddsam9a6y7RWWXq6K6Oe4Q-nh7fZy_54vV5Ppsucsu53OZKCKeWpTQCQEoJnBLLGKRRFS9VJStn9kwYnThVUmq5UiUGJiSjEi_pCN0fcjeh--pd3OrGR-vq2rSu66OWADwlqyTe_hPXXR_a9DcNBIRQGE-SBAfJhi7G4Cq9Cb4xYacJ1vtWNSZ6Nn9LCIn1vtV0dHNM7peNK_-cHGpMwt1RMNGaugqpIB9_PTYRghP6A4OUfEs</recordid><startdate>20000912</startdate><enddate>20000912</enddate><creator>TANAKA, Hirofumi</creator><creator>DINENNO, Frank A</creator><creator>MONAHAN, Kevin D</creator><creator>CLEVENGER, Christopher M</creator><creator>DESOUZA, Christopher A</creator><creator>SEALS, Douglas R</creator><general>Lippincott Williams & Wilkins</general><general>American Heart Association, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>20000912</creationdate><title>Aging, habitual exercise, and dynamic arterial compliance</title><author>TANAKA, Hirofumi ; DINENNO, Frank A ; MONAHAN, Kevin D ; CLEVENGER, Christopher M ; DESOUZA, Christopher A ; SEALS, Douglas R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c557t-966e9bd7a6227772531c4424249f5d9f7fea44241438e9d33c599d024674370b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aging - physiology</topic><topic>Arteries - physiology</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary heart disease</topic><topic>Cross-Sectional Studies</topic><topic>Elasticity</topic><topic>Exercise</topic><topic>Heart</topic><topic>Humans</topic><topic>Life Style</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Physical Endurance</topic><topic>Risk Factors</topic><topic>Thoracic Arteries - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TANAKA, Hirofumi</creatorcontrib><creatorcontrib>DINENNO, Frank A</creatorcontrib><creatorcontrib>MONAHAN, Kevin D</creatorcontrib><creatorcontrib>CLEVENGER, Christopher M</creatorcontrib><creatorcontrib>DESOUZA, Christopher A</creatorcontrib><creatorcontrib>SEALS, Douglas R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TANAKA, Hirofumi</au><au>DINENNO, Frank A</au><au>MONAHAN, Kevin D</au><au>CLEVENGER, Christopher M</au><au>DESOUZA, Christopher A</au><au>SEALS, Douglas R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aging, habitual exercise, and dynamic arterial compliance</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><addtitle>Circulation</addtitle><date>2000-09-12</date><risdate>2000</risdate><volume>102</volume><issue>11</issue><spage>1270</spage><epage>1275</epage><pages>1270-1275</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><coden>CIRCAZ</coden><abstract>A reduction in compliance of the large-sized cardiothoracic (central) arteries is an independent risk factor for the development of cardiovascular disease with advancing age.
We determined the role of habitual exercise on the age-related decrease in central arterial compliance by using both cross-sectional and interventional approaches. First, we studied 151 healthy men aged 18 to 77 years: 54 were sedentary, 45 were recreationally active, and 53 were endurance exercise-trained. Central arterial compliance (simultaneous B-mode ultrasound and arterial applanation tonometry on the common carotid artery) was lower (P:<0.05) in middle-aged and older men than in young men in all 3 groups. There were no significant differences between sedentary and recreationally active men at any age. However, arterial compliance in the endurance-trained middle-aged and older men was 20% to 35% higher than in the 2 less active groups (P:<0.01). As such, age-related differences in central arterial compliance were smaller in the endurance-trained men than in the sedentary and recreationally active men. Second, we studied 20 middle-aged and older (53+/-2 years) sedentary healthy men before and after a 3-month aerobic exercise intervention (primarily walking). Regular exercise increased central arterial compliance (P:<0.01) to levels similar to those of the middle-aged and older endurance-trained men. These effects were independent of changes in body mass, adiposity, arterial blood pressure, or maximal oxygen consumption.
Regular aerobic-endurance exercise attenuates age-related reductions in central arterial compliance and restores levels in previously sedentary healthy middle-aged and older men. This may be one mechanism by which habitual exercise lowers the risk of cardiovascular disease in this population.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>10982542</pmid><doi>10.1161/01.cir.102.11.1270</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | Journals@Ovid Ovid Autoload; MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Aged Aging - physiology Arteries - physiology Biological and medical sciences Cardiology. Vascular system Coronary heart disease Cross-Sectional Studies Elasticity Exercise Heart Humans Life Style Male Medical sciences Middle Aged Physical Endurance Risk Factors Thoracic Arteries - physiology |
| title | Aging, habitual exercise, and dynamic arterial compliance |
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