Chemiluminometric determination of reserpine and related alkaloids
The determination of the alkaloids reserpine, rescinnamine and yohimbine based on a chemiluminogenic reaction with potassium permanganate in the presence of polyphosphoric acid is described. The investigation was carried out using a batch and a flow injection chemiluminometer. Both approaches were a...
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| Veröffentlicht in: | Analyst (London) 2000-01, Vol.125 (7), p.1307-1311 |
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| container_title | Analyst (London) |
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| creator | PINOTSIS, N CALOKERINOS, A. C BAEYENS, W. R. G |
| description | The determination of the alkaloids reserpine, rescinnamine and yohimbine based on a chemiluminogenic reaction with potassium permanganate in the presence of polyphosphoric acid is described. The investigation was carried out using a batch and a flow injection chemiluminometer. Both approaches were accurate and precise, allowing the measurement of reserpine within the ranges 0.100-3.00 and 0.050-3.00 micrograms ml-1 with RSD values for 1.00 microgram ml-1 of 1.91 and 0.33% (n = 8) with the batch and the flow injection manifold, respectively. The procedure was successfully applied to formulations after extraction of reserpine with chloroform, with recoveries from commercial formulations within the range 95.2-99.0%. |
| doi_str_mv | 10.1039/b001430n |
| format | Article |
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The procedure was successfully applied to formulations after extraction of reserpine with chloroform, with recoveries from commercial formulations within the range 95.2-99.0%.</description><subject>Adrenergic alpha-Antagonists - analysis</subject><subject>Analysis</subject><subject>Biological and medical sciences</subject><subject>Flow Injection Analysis</subject><subject>General pharmacology</subject><subject>Luminescent Measurements</subject><subject>Medical sciences</subject><subject>Pharmacology. 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| ispartof | Analyst (London), 2000-01, Vol.125 (7), p.1307-1311 |
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| source | Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Adrenergic alpha-Antagonists - analysis Analysis Biological and medical sciences Flow Injection Analysis General pharmacology Luminescent Measurements Medical sciences Pharmacology. Drug treatments Reserpine - analogs & derivatives Reserpine - analysis Yohimbine - analysis |
| title | Chemiluminometric determination of reserpine and related alkaloids |
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