Antiarrhythmic and electrophysiological effects of GYKI-16638, a novel N-(phenoxyalkyl)- N-phenylalkylamine, in rabbits

The effect of N-[4-[2- N-methyl- N-[1-methyl-2-(2,6-dimethylphenoxy)ethylamino]-ethyl]-phenyl]-methanesulfonamide.hydrochloride (GYKI-16638; 0.03 and 0.1 mg/kg, i.v.), a novel antiarrhythmic compound, was assessed and compared to that of d-sotalol (1 and 3 mg/kg, i.v.) on arrhythmias induced by 10 m...

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