Does Histologic Grade Have a Role in the Management of Head and Neck Cancers?

High histologic grade is usually associated with a greater propensity to distant metastases (DM). Its role to predict DM in head and neck cancer is not yet defined. The aim of this study is to evaluate the role of histologic grade as an independent predictor of DM and to determine a subgroup of pati...

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Veröffentlicht in:	Journal of clinical oncology 2001-11, Vol.19 (21), p.4107-4116
Hauptverfasser:	FORTIN, André, COUTURE, Christian, DOUCET, René, ALBERT, Michele, ALLARD, Josée, TETU, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Combined Modality Therapy Female Glutathione S-Transferase pi Glutathione Transferase - metabolism Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - pathology Head and Neck Neoplasms - radiotherapy Head and Neck Neoplasms - surgery Humans Isoenzymes - metabolism Ki-67 Antigen - metabolism Male Medical sciences Middle Aged Neoplasm Metastasis Neoplasm Staging Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Proportional Hazards Models Retrospective Studies Survival Analysis Tumor Suppressor Protein p53 - metabolism Tumors
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