Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus

Many agents that influence serotonergic neurotransmission modulate expression of hippocampal corticosteroid receptors. We have studied the effect of the specific 5-hydroxytryptamine, 5-HT 1A, receptor agonist flesinoxan on mRNA for glucocorticoid and mineralocorticoid receptors in the hippocampus an...

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Veröffentlicht in:	European journal of pharmacology 2000-09, Vol.404 (1), p.111-119
Hauptverfasser:	Sibug, Rosana M, Compaan, Josje C, Meijer, Onno C, Van der Gugten, Jan, Olivier, Berend, Ron De Kloet, E
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT 1A receptor agonist Animals Biological and medical sciences Cell receptors Cell structures and functions Corticosterone - blood Dorsal raphe nucleus Flesinoxan Fundamental and applied biological sciences. Psychology Glucocorticoid receptor Hippocampus Hippocampus - drug effects Hippocampus - metabolism Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Lip - drug effects Lip - physiology Male Mineralocorticoid receptor Molecular and cellular biology Piperazines - administration & dosage Piperazines - pharmacology Rats Rats, Wistar - surgery Receptors, Mineralocorticoid - biosynthesis Receptors, Mineralocorticoid - genetics Receptors, Steroid - biosynthesis Receptors, Steroid - genetics RNA, Messenger - biosynthesis RNA, Messenger - drug effects Serotonin Receptor Agonists - administration & dosage Serotonin Receptor Agonists - pharmacology
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