Nonlymphoid reservoirs of HIV replication in children with chronic-progressive disease

Autopsy tissues from 2 cohorts of age‐matched HIV‐infected children with similar plasma viral load (>105 HIV RNA copies/ml), but with distinct AIDS‐associated disease manifestations, were examined for sites of persistent HIV replication. One group consisted of 3 children with severe lymphoid atro...

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Veröffentlicht in:	Journal of leukocyte biology 2000-09, Vol.68 (3), p.351-359
1. Verfasser:	Brodie, Scott J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - blood Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - virology AIDS-Related Opportunistic Infections - complications AIDS-Related Opportunistic Infections - virology AIDS/HIV Atrophy BALT CD4 Lymphocyte Count CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - virology Child Child, Preschool Dendritic Cells - virology Digestive System - virology DNA, Viral Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - virology follicular dendritic cells GALT Herpesviridae Infections - complications Herpesviridae Infections - virology Herpesvirus 4, Human - genetics Herpesvirus 8, Human - genetics HIV-1 - genetics HIV-1 - physiology Human immunodeficiency virus Humans Immunohistochemistry In Situ Hybridization Lung - virology Lymph Nodes - virology Lymphoid Tissue - pathology Lymphoid Tissue - virology Lymphoproliferative Disorders - complications Lymphoproliferative Disorders - virology macrophages Macrophages - virology peripheral blood lymphocytes Polymerase Chain Reaction RNA, Viral - blood RNA, Viral - metabolism Viral Load Virus Latency Virus Replication
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