Melatonin inhibits apoptosis during early B-cell development in mouse bone marrow

The pineal secretory product, melatonin, exerts a variety of effects on the immune system. Administration of melatonin stimulates cell‐mediated immunity, particularly by inhibiting apoptosis among T lymphocytes in the thymus and inducing production of T‐cell‐derived cytokines. However, its possible...

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Veröffentlicht in:	Journal of pineal research 2000-09, Vol.29 (2), p.86-93
Hauptverfasser:	Yu, Qingnan, Miller, Sandra C., Osmond, Dennis G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals apoptosis Apoptosis - drug effects Apoptosis - immunology B cell B-Lymphocytes - cytology B-Lymphocytes - drug effects B-Lymphocytes - physiology Biological and medical sciences bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - drug effects Bone Marrow Cells - physiology Cell Cycle - drug effects Cell Cycle - immunology Cell Differentiation - drug effects Cell Differentiation - immunology Cell Lineage - immunology Cells, Cultured DNA - metabolism Female Flow Cytometry Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Immunophenotyping melatonin Melatonin - metabolism Melatonin - pharmacology Mice Mice, Inbred C3H Organs and cells involved in the immune response pre-B cell Stem Cells - cytology Stem Cells - drug effects Stem Cells - physiology
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