Polyomavirus Enhancer-binding Protein 2/Core Binding Factor/Acute Myeloid Leukemia Factors Contribute to the Cell Type-specific Activity of the CD11a Integrin Gene Promoter

The CD11a/CD18 leukocyte integrin (LFA-1; also known as Î±L/Î²2) mediates leukocyte transendothelial migration during immune and inflammatory responses and participates in lymphoma metastasis. CD11a/CD18 leukocyte-restricted expression is controlled by the CD11a gene promoter, which confers tissue-s...

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Veröffentlicht in:	The Journal of biological chemistry 2000-09, Vol.275 (37), p.28507-28512
Hauptverfasser:	Puig-Kroeger, A, Lopez-Rodriguez, C, Relloso, M, Sanchez-Elsner, T, Nueda, A, Munoz, E, Bernabeu, C, Corbi, AL
Format:	Artikel
Sprache:	eng
Schlagworte:	AML1B protein CCAAT-Enhancer-Binding Proteins CD11a antigen Cell Line Core Binding Factor Alpha 2 Subunit core-binding factor DNA-Binding Proteins - physiology Humans Lymphocyte Function-Associated Antigen-1 - genetics Polyomavirus polyomavirus enhancer-binding protein 2 Promoter Regions, Genetic Proto-Oncogene Proteins Transcription Factor AP-2 Transcription Factors - physiology Transcriptional Activation
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