Sensitive and specific enzyme-linked immunosorbent assay for the diagnosis of Wuchereria bancrofti infection in urine samples

We developed an enzyme-linked immunosorbent assay (ELISA) that detects filaria-specific immunoglobulin G4 antibodies in unconcentrated urine. The ELISA was positive in 87 of 91 (95.6%) urine samples collected from people with Wuchereria bancrofti microfilariae, antigen, or both. Of 298 urine samples...

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Veröffentlicht in:	The American journal of tropical medicine and hygiene 2001-10, Vol.65 (4), p.362-365
Hauptverfasser:	Itoh, M, Weerasooriya, MV, Qiu, G, Gunawardena, NK, Anantaphruti, MT, Tesana, S, Rattanaxay, P, Fujimaki, Y, Kimura, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Helminth - urine Antigens, Helminth - analysis Biological and medical sciences Diseases caused by nematodes Elephantiasis, Filarial - diagnosis Elephantiasis, Filarial - urine Enzyme-Linked Immunosorbent Assay - methods Filariases Helminthic diseases Humans Immunoglobulin G - urine Infectious diseases Lymphatic filariases Medical sciences Parasitic diseases Sensitivity and Specificity Time Factors Tropical medicine Wuchereria bancrofti - immunology
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