Depolarization of the tegument precedes morphological alterations in Echinococcus granulosus protoscoleces incubated with ivermectin

The nematocidal activity of ivermectin (IVM) largely arises from its activity as a potent agonist of muscular and neuronal glutamate-gated chloride channels. A cestocidal effect has also been suggested following in vitro treatments, but the molecular basis of this activity is not clear. We studied t...

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Veröffentlicht in:	Parasitology research (1987) 2001-10, Vol.87 (10), p.804-807
Hauptverfasser:	PEREZ-SERRANO, Jorge, GROSMAN, Claudio, URREA-PARIS, Maria Angeles, DENEGRI, Guillermo, CASADO, Nieves, RODRIGUEZ-CAABEIRO, Filomena
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Anticestodal Agents - pharmacology Antiparasitic agents Biological and medical sciences Echinococcus - drug effects Echinococcus - physiology Echinococcus - ultrastructure Ivermectin - pharmacology Medical sciences Membrane Potentials Microscopy, Electron Microscopy, Electron, Scanning Pharmacology. Drug treatments
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