Protein delivery by Pseudomonas type III secretion system: Ex vivo complementation of p67(phox)-deficient chronic granulomatous disease

Bacterial type III secretion system drives the translocation of virulence factors into the cystosol of host target cells. In phagocytes and in Epstein-Barr virus immortalized B lymphocytes, NADPH oxidase generates O(-2) through an electron transfer chain the activity of which depends on the assembly...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2000-09, Vol.275 (3), p.854-858
Hauptverfasser:	Polack, B, Vergnaud, S, Paclet, M H, Lamotte, D, Toussaint, B, Morel, F
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - enzymology B-Lymphocytes - metabolism B-Lymphocytes - microbiology B-Lymphocytes - pathology Bacterial Proteins - genetics Bacterial Proteins - metabolism Biological Transport Cell Line, Transformed chronic granulomatous disease Cytosol - enzymology Cytosol - metabolism ExoS protein Genetic Complementation Test Granulomatous Disease, Chronic - enzymology Granulomatous Disease, Chronic - genetics Granulomatous Disease, Chronic - metabolism Herpesvirus 4, Human - genetics Herpesvirus 4, Human - physiology Histidine Kinase Humans NADPH oxidase NADPH Oxidases - metabolism Phosphoproteins - deficiency Phosphoproteins - genetics Phosphoproteins - metabolism protein delivery Protein Kinases - genetics Protein Kinases - metabolism Pseudomonas aeruginosa Pseudomonas aeruginosa - enzymology Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - metabolism Recombinant Fusion Proteins - metabolism Virulence - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!