In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea

The amino acid sequences of Gcd10p and Gcd14p, the two subunits of the tRNA:(1-methyladenosine-58; m 1A58) methyltransferase (MTase) of Saccharomyces cerevisiae, have been analyzed using iterative sequence database searches and fold recognition programs. The results suggest that the ‘catalytic’ Gcd1...

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Veröffentlicht in:	FEBS letters 2001-10, Vol.507 (2), p.123-127
1. Verfasser:	Bujnicki, Janusz M
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyladenosine Amino Acid Sequence Archaea - enzymology Eubacterium - enzymology Methyltransferase Molecular evolution Molecular Sequence Data Protein Folding Protein structure prediction RNA modification RNA, Transfer Sequence Analysis, Protein tRNA Methyltransferases - chemistry tRNA Methyltransferases - classification tRNA Methyltransferases - physiology
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