Catalytic, Asymmetric Synthesis of Siphonarienal

Catalytic, Asymmetric Synthesis of Siphonarienal

This paper describes the synthesis of the marine natural product, siphonarienal. The key step of this synthesis is an aldol reaction that constructs most of the skeleton and sets all three stereocenters of the target in one step from commercially available starting materials. Deoxygenation and chain...

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Veröffentlicht in:Journal of organic chemistry 2001-11, Vol.66 (22), p.7500-7504
Hauptverfasser: Calter, Michael A, Liao, Wensheng, Struss, John A
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Sprache:eng
Schlagworte:
Alkanes - chemical synthesis
Animals
Anti-Infective Agents - chemistry
Antineoplastic Agents - chemistry
Biological Factors - chemical synthesis
Biological Factors - chemistry
Catalysis
Molecular Structure
Mollusca - chemistry
Stereoisomerism
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container_title Journal of organic chemistry
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creator Calter, Michael A
Liao, Wensheng
Struss, John A
description This paper describes the synthesis of the marine natural product, siphonarienal. The key step of this synthesis is an aldol reaction that constructs most of the skeleton and sets all three stereocenters of the target in one step from commercially available starting materials. Deoxygenation and chain homologation steps complete the synthesis.
doi_str_mv 10.1021/jo0160367
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Org. Chem</addtitle><description>This paper describes the synthesis of the marine natural product, siphonarienal. The key step of this synthesis is an aldol reaction that constructs most of the skeleton and sets all three stereocenters of the target in one step from commercially available starting materials. 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subjects Alkanes - chemical synthesis
Animals
Anti-Infective Agents - chemistry
Antineoplastic Agents - chemistry
Biological Factors - chemical synthesis
Biological Factors - chemistry
Catalysis
Molecular Structure
Mollusca - chemistry
Stereoisomerism
title Catalytic, Asymmetric Synthesis of Siphonarienal
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