Severe congenital dyserythropoietic anaemia type I: prenatal management, transfusion support and alpha‐interferon therapy

We report a case of congenital dyserythropoietic anaemia, type I, with severe pre‐ and postnatal manifestations. Exchange transfusions were required for fetal anaemia (3·5 g/dl) at 28 and 30 weeks of gestation. Transfusions were administered at birth (Caesarean section at week 35) and at regular int...

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Veröffentlicht in:	British journal of haematology 2000-08, Vol.110 (2), p.420-423
Hauptverfasser:	Parez, N., Dommergues, M., Zupan, V., Chambost, H., Fieschi, J. B., Delaunay, J., Miélot, F., Cramer, E. M., Dommergues, J.‐P., Wickramasinghe, S. N., Tchernia, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia, Dyserythropoietic, Congenital - diagnosis Anemia, Dyserythropoietic, Congenital - therapy Anemias. Hemoglobinopathies Biological and medical sciences Bone Marrow Examination congenital dyserythropoietic anaemia Diseases of red blood cells Exchange Transfusion, Whole Blood - methods Female Hematologic and hematopoietic diseases Hematology Humans Infant Infant, Newborn Interferon alpha-2 Interferon-alpha - therapeutic use intrauterine transfusion Iron Overload - etiology Liver Function Tests Medical sciences Pregnancy Pregnancy Trimester, Second Pregnancy Trimester, Third prenatal diagnosis Prenatal Diagnosis - methods Recombinant Proteins Treatment Outcome α‐interferon
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