BIGH3 Gene Mutations and Rapid Detection in Korean Patients With Corneal Dystrophy

PURPOSE.Mutations in the BIGH3 gene on chromosome 5q31 cause four distinct autosomal dominant corneal dystrophies. We sought to determine whether the BIGH3 gene mutation was responsible for corneal dystrophy in Korean patients. METHODS.Polymerase chain reaction single strand conformational polymorph...

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