Vinyl and Alkynyl Pyrimidines as Michael Acceptors:  An Approach to a Cylindrospermopsin Substructure

Vinyl pyrimidine 9 and alkynyl pyrimidine 24 undergo base-mediated intramolecular conjugate addition reactions in which a carbamate and a urea, respectively, behave as nitrogen nucleophiles. The cyclic carbamate derived from 9 was converted to 11 via a metalation−oxidation reaction in which 2-phenyl...

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Veröffentlicht in:	Journal of organic chemistry 2000-09, Vol.65 (18), p.5668-5675
Hauptverfasser:	Djung, Jane F, Hart, David J, Young, Erick R. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Toxins Magnetic Resonance Spectroscopy Spectrophotometry, Infrared Uracil - analogs & derivatives Uracil - chemistry
Online-Zugang:	Volltext
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