Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura

Thrombotic thrombocytopenic purpura is associated with acquired or congenital deficiency of a plasma von Willebrand factor-cleaving protease (VWFCP). Based on partial amino acid sequence, VWFCP was identified recently as a new member of the ADAMTS family of metalloproteases and designated ADAMTS13....

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Veröffentlicht in:	The Journal of biological chemistry 2001-11, Vol.276 (44), p.41059-41063
Hauptverfasser:	Zheng, Xinglong, Chung, Dominic, Takayama, Thomas K., Majerus, Elaine M., Sadler, J. Evan, Fujikawa, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Blotting, Northern Cloning, Molecular DNA, Complementary Humans Liver - enzymology Metalloendopeptidases - chemistry Metalloendopeptidases - genetics Metalloendopeptidases - metabolism Molecular Sequence Data Protein Conformation Purpura, Thrombotic Thrombocytopenic - enzymology RNA, Messenger - isolation & purification Sequence Homology, Amino Acid
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