Effects of thiopental and its optical isomers on nicotinic acetylcholine receptors

With the exception of gamma-aminobutyric acidA (GABAA) receptors, the major molecular targets underlying the anesthetizing actions of thiopental have yet to be established. Neuronal nicotinic acetylcholine receptors (nAChRs) are closely related to GABAA receptors and hence might also be major target...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2000-09, Vol.93 (3), p.774-783
Hauptverfasser:	DOWNIE, David L, FRANKS, Nicholas P, LIEB, William R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Anesthetics, Intravenous - pharmacology Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Dose-Response Relationship, Drug Female Ion Channels - drug effects Medical sciences Neuropharmacology Pharmacology. Drug treatments Receptors, Nicotinic - drug effects Receptors, Nicotinic - physiology Stereoisomerism Thiopental - pharmacology Xenopus laevis
Online-Zugang:	Volltext
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