Daily Multivitamins with Iron to Prevent Anemia in Infancy: A Randomized Clinical Trial
This study assessed the effectiveness of multivitamins (MV) with iron as prophylaxis against iron deficiency (ID) and anemia in infancy. The study was a double-blind, randomized trial at 2 urban primary care clinics. Subjects included healthy, full-term infants enrolled at their 6-month well-child v...
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| Veröffentlicht in: | Clinical pediatrics 2001-10, Vol.40 (10), p.549-554 |
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| creator | Geltman, Paul L. Meyers, Alan F. Bauchner, Howard |
| description | This study assessed the effectiveness of multivitamins (MV) with iron as prophylaxis against iron deficiency (ID) and anemia in infancy. The study was a double-blind, randomized trial at 2 urban primary care clinics. Subjects included healthy, full-term infants enrolled at their 6-month well-child visit. Parents administered MV, either with iron or without iron, by mouth daily for 3 months. At 9 months of age, 28.3% of 310 had either anemia or ID without anemia. Among infants with any adherence, anemia was found in 11.1% of the iron group and 21.7% in the noniron group (RR=0.5, 95% CI=0.3-1.0). Iron deficiency without anemia was found in 18.5% of the iron group; 14.4% of the noniron group (p=0.46). When administered daily starting at age 6 months, standard-dose multivitamins with iron appear to reduce anemia prevalence at 9 months of age. |
| doi_str_mv | 10.1177/000992280104001003 |
| format | Article |
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The study was a double-blind, randomized trial at 2 urban primary care clinics. Subjects included healthy, full-term infants enrolled at their 6-month well-child visit. Parents administered MV, either with iron or without iron, by mouth daily for 3 months. At 9 months of age, 28.3% of 310 had either anemia or ID without anemia. Among infants with any adherence, anemia was found in 11.1% of the iron group and 21.7% in the noniron group (RR=0.5, 95% CI=0.3-1.0). Iron deficiency without anemia was found in 18.5% of the iron group; 14.4% of the noniron group (p=0.46). When administered daily starting at age 6 months, standard-dose multivitamins with iron appear to reduce anemia prevalence at 9 months of age.</description><identifier>ISSN: 0009-9228</identifier><identifier>EISSN: 1938-2707</identifier><identifier>DOI: 10.1177/000992280104001003</identifier><identifier>PMID: 11681821</identifier><identifier>CODEN: CPEDAM</identifier><language>eng</language><publisher>708 Glen Cove Avenue, Glen Head, NY 11545: SAGE Publications</publisher><subject>Anemia, Iron-Deficiency - prevention & control ; Anemias. Hemoglobinopathies ; Animals ; Biological and medical sciences ; Breast Feeding ; Children ; Diseases ; Diseases of red blood cells ; Double-Blind Method ; Drug Combinations ; Female ; General and cellular metabolism. Vitamins ; Hematologic and hematopoietic diseases ; Humans ; Infant ; Iron - therapeutic use ; Iron deficiency anemia ; Iron deficiency anemia in children ; Male ; Medical sciences ; Patient Compliance ; Pharmacology. Drug treatments ; Prevention ; Vitamins - therapeutic use</subject><ispartof>Clinical pediatrics, 2001-10, Vol.40 (10), p.549-554</ispartof><rights>2002 INIST-CNRS</rights><rights>COPYRIGHT 2001 Sage Publications, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-e33b5aa2421e3d3b8fc64f9deae0f6ff9c46606df27c879c378c9f44ef4deef93</citedby><cites>FETCH-LOGICAL-c444t-e33b5aa2421e3d3b8fc64f9deae0f6ff9c46606df27c879c378c9f44ef4deef93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/000992280104001003$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/000992280104001003$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21799,27903,27904,43600,43601</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14158582$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11681821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Geltman, Paul L.</creatorcontrib><creatorcontrib>Meyers, Alan F.</creatorcontrib><creatorcontrib>Bauchner, Howard</creatorcontrib><title>Daily Multivitamins with Iron to Prevent Anemia in Infancy: A Randomized Clinical Trial</title><title>Clinical pediatrics</title><addtitle>Clin Pediatr (Phila)</addtitle><description>This study assessed the effectiveness of multivitamins (MV) with iron as prophylaxis against iron deficiency (ID) and anemia in infancy. The study was a double-blind, randomized trial at 2 urban primary care clinics. Subjects included healthy, full-term infants enrolled at their 6-month well-child visit. Parents administered MV, either with iron or without iron, by mouth daily for 3 months. At 9 months of age, 28.3% of 310 had either anemia or ID without anemia. Among infants with any adherence, anemia was found in 11.1% of the iron group and 21.7% in the noniron group (RR=0.5, 95% CI=0.3-1.0). Iron deficiency without anemia was found in 18.5% of the iron group; 14.4% of the noniron group (p=0.46). When administered daily starting at age 6 months, standard-dose multivitamins with iron appear to reduce anemia prevalence at 9 months of age.</description><subject>Anemia, Iron-Deficiency - prevention & control</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Breast Feeding</subject><subject>Children</subject><subject>Diseases</subject><subject>Diseases of red blood cells</subject><subject>Double-Blind Method</subject><subject>Drug Combinations</subject><subject>Female</subject><subject>General and cellular metabolism. Vitamins</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Iron - therapeutic use</subject><subject>Iron deficiency anemia</subject><subject>Iron deficiency anemia in children</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Patient Compliance</subject><subject>Pharmacology. Drug treatments</subject><subject>Prevention</subject><subject>Vitamins - therapeutic use</subject><issn>0009-9228</issn><issn>1938-2707</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90V1rFDEUBuAgil2rf8ALyY1eOTZfM8l4t6xfCy0VqXg5nM2crCmZTE1mKuuvb5Zd6IWlBBIIzzkJ7yHkNWcfONf6jDHWtkIYxpliZWPyCVnwVppKaKafksUeVHtxQl7kfF2MZLV8Tk44bww3gi_Ir0_gw45ezGHyt36CwcdM__rpN12nMdJppN8T3mKc6DLi4IH6SNfRQbS7j3RJf0Dsx8H_w56ugo_eQqBXyUN4SZ45CBlfHc9T8vPL56vVt-r88ut6tTyvrFJqqlDKTQ0glOAoe7kxzjbKtT0CMtc411rVNKzpndDW6NZKbWzrlEKnekTXylPy7tD3Jo1_ZsxTN_hsMQSIOM6500JILqUp8P0BbiFg56MbpwR2ixEThDGi8-V6WbKstRT7vtUDvKy-pGAf8uLgbRpzTui6m-QHSLuOs24_re7_aZWiN8fPz5sB-_uS43gKeHsEkEu0LpXcfb53itemNqK4s4PLsMXuepxTLKE_9vQdy8ao4Q</recordid><startdate>20011001</startdate><enddate>20011001</enddate><creator>Geltman, Paul L.</creator><creator>Meyers, Alan F.</creator><creator>Bauchner, Howard</creator><general>SAGE Publications</general><general>Westminster</general><general>Sage Publications, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011001</creationdate><title>Daily Multivitamins with Iron to Prevent Anemia in Infancy: A Randomized Clinical Trial</title><author>Geltman, Paul L. ; Meyers, Alan F. ; Bauchner, Howard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-e33b5aa2421e3d3b8fc64f9deae0f6ff9c46606df27c879c378c9f44ef4deef93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Anemia, Iron-Deficiency - prevention & control</topic><topic>Anemias. Hemoglobinopathies</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Breast Feeding</topic><topic>Children</topic><topic>Diseases</topic><topic>Diseases of red blood cells</topic><topic>Double-Blind Method</topic><topic>Drug Combinations</topic><topic>Female</topic><topic>General and cellular metabolism. Vitamins</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Infant</topic><topic>Iron - therapeutic use</topic><topic>Iron deficiency anemia</topic><topic>Iron deficiency anemia in children</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Patient Compliance</topic><topic>Pharmacology. Drug treatments</topic><topic>Prevention</topic><topic>Vitamins - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Geltman, Paul L.</creatorcontrib><creatorcontrib>Meyers, Alan F.</creatorcontrib><creatorcontrib>Bauchner, Howard</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Geltman, Paul L.</au><au>Meyers, Alan F.</au><au>Bauchner, Howard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Daily Multivitamins with Iron to Prevent Anemia in Infancy: A Randomized Clinical Trial</atitle><jtitle>Clinical pediatrics</jtitle><addtitle>Clin Pediatr (Phila)</addtitle><date>2001-10-01</date><risdate>2001</risdate><volume>40</volume><issue>10</issue><spage>549</spage><epage>554</epage><pages>549-554</pages><issn>0009-9228</issn><eissn>1938-2707</eissn><coden>CPEDAM</coden><abstract>This study assessed the effectiveness of multivitamins (MV) with iron as prophylaxis against iron deficiency (ID) and anemia in infancy. The study was a double-blind, randomized trial at 2 urban primary care clinics. Subjects included healthy, full-term infants enrolled at their 6-month well-child visit. Parents administered MV, either with iron or without iron, by mouth daily for 3 months. At 9 months of age, 28.3% of 310 had either anemia or ID without anemia. Among infants with any adherence, anemia was found in 11.1% of the iron group and 21.7% in the noniron group (RR=0.5, 95% CI=0.3-1.0). Iron deficiency without anemia was found in 18.5% of the iron group; 14.4% of the noniron group (p=0.46). When administered daily starting at age 6 months, standard-dose multivitamins with iron appear to reduce anemia prevalence at 9 months of age.</abstract><cop>708 Glen Cove Avenue, Glen Head, NY 11545</cop><pub>SAGE Publications</pub><pmid>11681821</pmid><doi>10.1177/000992280104001003</doi><tpages>6</tpages></addata></record> |
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| subjects | Anemia, Iron-Deficiency - prevention & control Anemias. Hemoglobinopathies Animals Biological and medical sciences Breast Feeding Children Diseases Diseases of red blood cells Double-Blind Method Drug Combinations Female General and cellular metabolism. Vitamins Hematologic and hematopoietic diseases Humans Infant Iron - therapeutic use Iron deficiency anemia Iron deficiency anemia in children Male Medical sciences Patient Compliance Pharmacology. Drug treatments Prevention Vitamins - therapeutic use |
| title | Daily Multivitamins with Iron to Prevent Anemia in Infancy: A Randomized Clinical Trial |
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