Comparison of Bioabsorbable and Non‐Resorbable Membranes in the Treatment of Dehiscence‐Type Defects. A Histomorphometric Study in Dogs
Background: The goal of this investigation was to compare, histologically and histometrically, the healing process of dehiscence‐type defects treated by guided tissue regeneration (GTR) with bioabsorbable polylactic acid (PLA) membranes and nonresorbable expanded polytetrafluoroethylene (ePTF) membr...
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| Veröffentlicht in: | Journal of periodontology (1970) 2000-08, Vol.71 (8), p.1306-1314 |
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| container_title | Journal of periodontology (1970) |
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| creator | Silva Pereira, Sergio L. Sallum, Antonio Wilson Casati, Marcio Z. Caffesse, Raul G. Weng, Dietmar Nociti, Francisco H. Sallum, Enilson A. |
| description | Background: The goal of this investigation was to compare, histologically and histometrically, the healing process of dehiscence‐type defects treated by guided tissue regeneration (GTR) with bioabsorbable polylactic acid (PLA) membranes and nonresorbable expanded polytetrafluoroethylene (ePTF) membranes.
Methods: Six mongrel dogs were used. Buccal osseous dehiscences were surgically created on the distal roots of the mandibular third and fourth premolars. The defects were exposed to plaque accumulation for 3 months. After this period, the defects were randomly assigned to one of the treatments: GTR with bioabsorbable membrane (PLA), GTR with non‐resorbable membrane (ePTFE), open flap debridement (OFD), and non‐treated control (NTC). After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included: gingival recession, epithelial length, connective tissue adaptation, new cementum, and new bone area.
Results: A superior length of new cementum was observed in the sites treated by GTR, regardless of the type of barrier used, in comparison with OFD (P |
| doi_str_mv | 10.1902/jop.2000.71.8.1306 |
| format | Article |
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Methods: Six mongrel dogs were used. Buccal osseous dehiscences were surgically created on the distal roots of the mandibular third and fourth premolars. The defects were exposed to plaque accumulation for 3 months. After this period, the defects were randomly assigned to one of the treatments: GTR with bioabsorbable membrane (PLA), GTR with non‐resorbable membrane (ePTFE), open flap debridement (OFD), and non‐treated control (NTC). After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included: gingival recession, epithelial length, connective tissue adaptation, new cementum, and new bone area.
Results: A superior length of new cementum was observed in the sites treated by GTR, regardless of the type of barrier used, in comparison with OFD (P <0.05). No statistically significant differences were found between PLA and ePTFE in any of the parameters with the exception of bone area. PLA presented a greater bone area when compared to ePTFE, OFD, and NTC (P <0.05).
Conclusions: Within the limits of this study, it can be concluded that both barriers are equally effective for new cementum formation. The bioabsorbable membrane may provide a greater bone area than the non‐resorbable membrane. J Periodontol 2000;71:1306‐1314.</description><identifier>ISSN: 0022-3492</identifier><identifier>EISSN: 1943-3670</identifier><identifier>DOI: 10.1902/jop.2000.71.8.1306</identifier><identifier>PMID: 10972646</identifier><language>eng</language><publisher>737 N. Michigan Avenue, Suite 800, Chicago, IL 60611‐2690, USA: American Academy of Periodontology</publisher><subject>Absorbable Implants ; Alveolar Bone Loss - pathology ; Alveolar Bone Loss - surgery ; Alveolar Process - pathology ; Analysis of Variance ; Animal studies ; Animals ; Connective Tissue - pathology ; Debridement ; Dental Cementum - pathology ; Dental Plaque - physiopathology ; Dentistry ; Dogs ; Epithelium - pathology ; Female ; Gingival Recession - pathology ; guided tissue regeneration ; Guided Tissue Regeneration, Periodontal - instrumentation ; Lactic Acid - chemistry ; Membranes, Artificial ; membranes, barrier ; membranes, bioabsorbable ; periodontal disease/surgery ; periodontal diseases/therapy ; Periodontal Ligament - pathology ; Polyesters ; polylactic acid/therapeutic use ; Polymers - chemistry ; Polytetrafluoroethylene - chemistry ; polytetrafluoroethylene/therapeutic use ; Random Allocation ; Statistics, Nonparametric ; Tooth Root - pathology ; Wound Healing</subject><ispartof>Journal of periodontology (1970), 2000-08, Vol.71 (8), p.1306-1314</ispartof><rights>2000 American Academy of Periodontology</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3486-e01ad7b1f6ec002e5cebc217ee86492e32c893620e3ee7622e5b6335e93fafa23</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1902%2Fjop.2000.71.8.1306$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1902%2Fjop.2000.71.8.1306$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10972646$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silva Pereira, Sergio L.</creatorcontrib><creatorcontrib>Sallum, Antonio Wilson</creatorcontrib><creatorcontrib>Casati, Marcio Z.</creatorcontrib><creatorcontrib>Caffesse, Raul G.</creatorcontrib><creatorcontrib>Weng, Dietmar</creatorcontrib><creatorcontrib>Nociti, Francisco H.</creatorcontrib><creatorcontrib>Sallum, Enilson A.</creatorcontrib><title>Comparison of Bioabsorbable and Non‐Resorbable Membranes in the Treatment of Dehiscence‐Type Defects. A Histomorphometric Study in Dogs</title><title>Journal of periodontology (1970)</title><addtitle>J Periodontol</addtitle><description>Background: The goal of this investigation was to compare, histologically and histometrically, the healing process of dehiscence‐type defects treated by guided tissue regeneration (GTR) with bioabsorbable polylactic acid (PLA) membranes and nonresorbable expanded polytetrafluoroethylene (ePTF) membranes.
Methods: Six mongrel dogs were used. Buccal osseous dehiscences were surgically created on the distal roots of the mandibular third and fourth premolars. The defects were exposed to plaque accumulation for 3 months. After this period, the defects were randomly assigned to one of the treatments: GTR with bioabsorbable membrane (PLA), GTR with non‐resorbable membrane (ePTFE), open flap debridement (OFD), and non‐treated control (NTC). After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included: gingival recession, epithelial length, connective tissue adaptation, new cementum, and new bone area.
Results: A superior length of new cementum was observed in the sites treated by GTR, regardless of the type of barrier used, in comparison with OFD (P <0.05). No statistically significant differences were found between PLA and ePTFE in any of the parameters with the exception of bone area. PLA presented a greater bone area when compared to ePTFE, OFD, and NTC (P <0.05).
Conclusions: Within the limits of this study, it can be concluded that both barriers are equally effective for new cementum formation. The bioabsorbable membrane may provide a greater bone area than the non‐resorbable membrane. J Periodontol 2000;71:1306‐1314.</description><subject>Absorbable Implants</subject><subject>Alveolar Bone Loss - pathology</subject><subject>Alveolar Bone Loss - surgery</subject><subject>Alveolar Process - pathology</subject><subject>Analysis of Variance</subject><subject>Animal studies</subject><subject>Animals</subject><subject>Connective Tissue - pathology</subject><subject>Debridement</subject><subject>Dental Cementum - pathology</subject><subject>Dental Plaque - physiopathology</subject><subject>Dentistry</subject><subject>Dogs</subject><subject>Epithelium - pathology</subject><subject>Female</subject><subject>Gingival Recession - pathology</subject><subject>guided tissue regeneration</subject><subject>Guided Tissue Regeneration, Periodontal - instrumentation</subject><subject>Lactic Acid - chemistry</subject><subject>Membranes, Artificial</subject><subject>membranes, barrier</subject><subject>membranes, bioabsorbable</subject><subject>periodontal disease/surgery</subject><subject>periodontal diseases/therapy</subject><subject>Periodontal Ligament - pathology</subject><subject>Polyesters</subject><subject>polylactic acid/therapeutic use</subject><subject>Polymers - chemistry</subject><subject>Polytetrafluoroethylene - chemistry</subject><subject>polytetrafluoroethylene/therapeutic use</subject><subject>Random Allocation</subject><subject>Statistics, Nonparametric</subject><subject>Tooth Root - pathology</subject><subject>Wound Healing</subject><issn>0022-3492</issn><issn>1943-3670</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkTtPwzAUhS0EoqXwBxiQJ7YEP4KTjKXlqfIQlNly3BuaKomDnQp1Y2fhN_JLcGiFGJmufHXOp3t8EDqkJKQpYScL04SMEBLGNExCyonYQn2aRjzgIibbqE8IYwGPUtZDe84t_JNGnOyiHiVpzEQk-uhjZKpG2cKZGpscnxVGZc7YTGUlYFXP8J2pv94_H-F3eQtVZlUNDhc1bueApxZUW0HddoAxzAunodbgXdNVA36Tg25diIf4qnCtqYxt5qaC1hYaP7XL2aoDjc2L20c7uSodHGzmAD1fnE9HV8Hk_vJ6NJwEmkeJCIBQNYszmgvQPhKcasg0ozFAInxW4EwnKReMAAeIBfOKTHB-CinPVa4YH6DjNbex5nUJrpVVd3NZ-lRm6WTMGCdRmnghWwu1Nc5ZyGVji0rZlaREdhVIX4HsKpAxlYnsKvCmow19mVUw-2NZ_7kXJGvBW1HC6h9IefNw_vjD_gYPhZeZ</recordid><startdate>200008</startdate><enddate>200008</enddate><creator>Silva Pereira, Sergio L.</creator><creator>Sallum, Antonio Wilson</creator><creator>Casati, Marcio Z.</creator><creator>Caffesse, Raul G.</creator><creator>Weng, Dietmar</creator><creator>Nociti, Francisco H.</creator><creator>Sallum, Enilson A.</creator><general>American Academy of Periodontology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200008</creationdate><title>Comparison of Bioabsorbable and Non‐Resorbable Membranes in the Treatment of Dehiscence‐Type Defects. A Histomorphometric Study in Dogs</title><author>Silva Pereira, Sergio L. ; Sallum, Antonio Wilson ; Casati, Marcio Z. ; Caffesse, Raul G. ; Weng, Dietmar ; Nociti, Francisco H. ; Sallum, Enilson A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3486-e01ad7b1f6ec002e5cebc217ee86492e32c893620e3ee7622e5b6335e93fafa23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Absorbable Implants</topic><topic>Alveolar Bone Loss - pathology</topic><topic>Alveolar Bone Loss - surgery</topic><topic>Alveolar Process - pathology</topic><topic>Analysis of Variance</topic><topic>Animal studies</topic><topic>Animals</topic><topic>Connective Tissue - pathology</topic><topic>Debridement</topic><topic>Dental Cementum - pathology</topic><topic>Dental Plaque - physiopathology</topic><topic>Dentistry</topic><topic>Dogs</topic><topic>Epithelium - pathology</topic><topic>Female</topic><topic>Gingival Recession - pathology</topic><topic>guided tissue regeneration</topic><topic>Guided Tissue Regeneration, Periodontal - instrumentation</topic><topic>Lactic Acid - chemistry</topic><topic>Membranes, Artificial</topic><topic>membranes, barrier</topic><topic>membranes, bioabsorbable</topic><topic>periodontal disease/surgery</topic><topic>periodontal diseases/therapy</topic><topic>Periodontal Ligament - pathology</topic><topic>Polyesters</topic><topic>polylactic acid/therapeutic use</topic><topic>Polymers - chemistry</topic><topic>Polytetrafluoroethylene - chemistry</topic><topic>polytetrafluoroethylene/therapeutic use</topic><topic>Random Allocation</topic><topic>Statistics, Nonparametric</topic><topic>Tooth Root - pathology</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silva Pereira, Sergio L.</creatorcontrib><creatorcontrib>Sallum, Antonio Wilson</creatorcontrib><creatorcontrib>Casati, Marcio Z.</creatorcontrib><creatorcontrib>Caffesse, Raul G.</creatorcontrib><creatorcontrib>Weng, Dietmar</creatorcontrib><creatorcontrib>Nociti, Francisco H.</creatorcontrib><creatorcontrib>Sallum, Enilson A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of periodontology (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silva Pereira, Sergio L.</au><au>Sallum, Antonio Wilson</au><au>Casati, Marcio Z.</au><au>Caffesse, Raul G.</au><au>Weng, Dietmar</au><au>Nociti, Francisco H.</au><au>Sallum, Enilson A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Bioabsorbable and Non‐Resorbable Membranes in the Treatment of Dehiscence‐Type Defects. A Histomorphometric Study in Dogs</atitle><jtitle>Journal of periodontology (1970)</jtitle><addtitle>J Periodontol</addtitle><date>2000-08</date><risdate>2000</risdate><volume>71</volume><issue>8</issue><spage>1306</spage><epage>1314</epage><pages>1306-1314</pages><issn>0022-3492</issn><eissn>1943-3670</eissn><abstract>Background: The goal of this investigation was to compare, histologically and histometrically, the healing process of dehiscence‐type defects treated by guided tissue regeneration (GTR) with bioabsorbable polylactic acid (PLA) membranes and nonresorbable expanded polytetrafluoroethylene (ePTF) membranes.
Methods: Six mongrel dogs were used. Buccal osseous dehiscences were surgically created on the distal roots of the mandibular third and fourth premolars. The defects were exposed to plaque accumulation for 3 months. After this period, the defects were randomly assigned to one of the treatments: GTR with bioabsorbable membrane (PLA), GTR with non‐resorbable membrane (ePTFE), open flap debridement (OFD), and non‐treated control (NTC). After 3 months of healing, the dogs were sacrificed and the blocks were processed. The histometric parameters evaluated included: gingival recession, epithelial length, connective tissue adaptation, new cementum, and new bone area.
Results: A superior length of new cementum was observed in the sites treated by GTR, regardless of the type of barrier used, in comparison with OFD (P <0.05). No statistically significant differences were found between PLA and ePTFE in any of the parameters with the exception of bone area. PLA presented a greater bone area when compared to ePTFE, OFD, and NTC (P <0.05).
Conclusions: Within the limits of this study, it can be concluded that both barriers are equally effective for new cementum formation. The bioabsorbable membrane may provide a greater bone area than the non‐resorbable membrane. J Periodontol 2000;71:1306‐1314.</abstract><cop>737 N. Michigan Avenue, Suite 800, Chicago, IL 60611‐2690, USA</cop><pub>American Academy of Periodontology</pub><pmid>10972646</pmid><doi>10.1902/jop.2000.71.8.1306</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0022-3492 |
| ispartof | Journal of periodontology (1970), 2000-08, Vol.71 (8), p.1306-1314 |
| issn | 0022-3492 1943-3670 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Absorbable Implants Alveolar Bone Loss - pathology Alveolar Bone Loss - surgery Alveolar Process - pathology Analysis of Variance Animal studies Animals Connective Tissue - pathology Debridement Dental Cementum - pathology Dental Plaque - physiopathology Dentistry Dogs Epithelium - pathology Female Gingival Recession - pathology guided tissue regeneration Guided Tissue Regeneration, Periodontal - instrumentation Lactic Acid - chemistry Membranes, Artificial membranes, barrier membranes, bioabsorbable periodontal disease/surgery periodontal diseases/therapy Periodontal Ligament - pathology Polyesters polylactic acid/therapeutic use Polymers - chemistry Polytetrafluoroethylene - chemistry polytetrafluoroethylene/therapeutic use Random Allocation Statistics, Nonparametric Tooth Root - pathology Wound Healing |
| title | Comparison of Bioabsorbable and Non‐Resorbable Membranes in the Treatment of Dehiscence‐Type Defects. A Histomorphometric Study in Dogs |
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