Mitral Balloon Valvotomy for the Treatment of Mitral Stenosis in Octogenarians

OBJECTIVES: To study the safety and benefit of mitral balloon valvotomy (MBV) in patients aged ≥ 80 years. SETTING: A tertiary cardiac centre DESIGN: A retrospective study of 20 octogenarians (mean age 83, range 80–89 years) in whom percutaneous MBV was performed as a definitive or palliative treatm...

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Veröffentlicht in:Journal of the American Geriatrics Society 2000-08, Vol.48 (8), p.971-974
Hauptverfasser: Sutaria, Nilesh, Elder, Andrew T., Shaw, Thomas R. D.
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container_title Journal of the American Geriatrics Society
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creator Sutaria, Nilesh
Elder, Andrew T.
Shaw, Thomas R. D.
description OBJECTIVES: To study the safety and benefit of mitral balloon valvotomy (MBV) in patients aged ≥ 80 years. SETTING: A tertiary cardiac centre DESIGN: A retrospective study of 20 octogenarians (mean age 83, range 80–89 years) in whom percutaneous MBV was performed as a definitive or palliative treatment for severe mitral stenosis. All were in New York Heart Association (NYHA) symptom class III or IV. Fourteen had been judged unfit for cardiac surgery. Hemodynamic data was recorded before and after MBV. Symptomatic outcome was documented at 1 month for all patients. Outcome at 1 year was available for 16 patients. RESULTS: Dilatation of the mitral valve was achieved in all patients without major complications. Mean mitral valve area increased 106% from 0.81 (± 0.3) to 1.67 (± 0.8) cm2, transvalvular gradient decreased from 11.8 (± 4.8) to 5.6 (± 2.9) mm Hg, cardiac output increased from 3.1 (± 0.6) to 4.1 (± 1.4) 1/min (all P < .01). Eight of these 20 patients obtained a valve area ≥ 1.5 cm2, and 16 obtained an area ≥ 1.2 cm2. One month after BMV, all patients were alive, and 16 of the 20 patients were improved by at least one NYHA class. This improvement was sustained in 7 of 16 patients followed up for 1 year. More severe mitral valve degenerative change, determined by echocardiography, was associated with poorer outcome. CONCLUSIONS: In this group of very old and frail patients, MBV was safe and resulted in significant immediate improvement. Sustained symptomatic benefit at 1 year was obtained in those with less extensive leaflet and subvalvular disease. In patients with severe degenerative valve disease on echocardiography, but unacceptable surgical risk, MBV offers short‐term palliation. J Am Geriatr Soc 48:971–974, 2000.
doi_str_mv 10.1111/j.1532-5415.2000.tb06897.x
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D.</creator><creatorcontrib>Sutaria, Nilesh ; Elder, Andrew T. ; Shaw, Thomas R. D.</creatorcontrib><description>OBJECTIVES: To study the safety and benefit of mitral balloon valvotomy (MBV) in patients aged ≥ 80 years. SETTING: A tertiary cardiac centre DESIGN: A retrospective study of 20 octogenarians (mean age 83, range 80–89 years) in whom percutaneous MBV was performed as a definitive or palliative treatment for severe mitral stenosis. All were in New York Heart Association (NYHA) symptom class III or IV. Fourteen had been judged unfit for cardiac surgery. Hemodynamic data was recorded before and after MBV. Symptomatic outcome was documented at 1 month for all patients. Outcome at 1 year was available for 16 patients. RESULTS: Dilatation of the mitral valve was achieved in all patients without major complications. Mean mitral valve area increased 106% from 0.81 (± 0.3) to 1.67 (± 0.8) cm2, transvalvular gradient decreased from 11.8 (± 4.8) to 5.6 (± 2.9) mm Hg, cardiac output increased from 3.1 (± 0.6) to 4.1 (± 1.4) 1/min (all P &lt; .01). Eight of these 20 patients obtained a valve area ≥ 1.5 cm2, and 16 obtained an area ≥ 1.2 cm2. One month after BMV, all patients were alive, and 16 of the 20 patients were improved by at least one NYHA class. This improvement was sustained in 7 of 16 patients followed up for 1 year. More severe mitral valve degenerative change, determined by echocardiography, was associated with poorer outcome. CONCLUSIONS: In this group of very old and frail patients, MBV was safe and resulted in significant immediate improvement. Sustained symptomatic benefit at 1 year was obtained in those with less extensive leaflet and subvalvular disease. In patients with severe degenerative valve disease on echocardiography, but unacceptable surgical risk, MBV offers short‐term palliation. J Am Geriatr Soc 48:971–974, 2000.</description><identifier>ISSN: 0002-8614</identifier><identifier>EISSN: 1532-5415</identifier><identifier>DOI: 10.1111/j.1532-5415.2000.tb06897.x</identifier><identifier>PMID: 10968304</identifier><identifier>CODEN: JAGSAF</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Activities of Daily Living ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Cardiology. Vascular system ; Cardiovascular disease ; Catheterization - adverse effects ; Catheterization - methods ; Comorbidity ; Echocardiography ; Endocardial and cardiac valvular diseases ; Female ; Frail Elderly ; Geriatric Assessment ; Geriatrics ; Heart ; Hemodynamics ; Humans ; Male ; Medical sciences ; mitral balloon valvotomy ; mitral stenosis ; Mitral Valve Stenosis - classification ; Mitral Valve Stenosis - diagnostic imaging ; Mitral Valve Stenosis - physiopathology ; Mitral Valve Stenosis - therapy ; octogenarian ; Older people ; Patient Selection ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Severity of Illness Index ; Surgery ; Treatment Outcome</subject><ispartof>Journal of the American Geriatrics Society, 2000-08, Vol.48 (8), p.971-974</ispartof><rights>2000 The American Geriatrics Society</rights><rights>2000 INIST-CNRS</rights><rights>Copyright Lippincott Williams &amp; Wilkins Aug 2000</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4657-dbd97ea63ea369006a74890bfe66580fe973741fbf370d0d7c23c09521e9282b3</citedby><cites>FETCH-LOGICAL-c4657-dbd97ea63ea369006a74890bfe66580fe973741fbf370d0d7c23c09521e9282b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1532-5415.2000.tb06897.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1532-5415.2000.tb06897.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>309,310,314,778,782,787,788,1414,23913,23914,25123,27907,27908,45557,45558</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=1510095$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10968304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sutaria, Nilesh</creatorcontrib><creatorcontrib>Elder, Andrew T.</creatorcontrib><creatorcontrib>Shaw, Thomas R. D.</creatorcontrib><title>Mitral Balloon Valvotomy for the Treatment of Mitral Stenosis in Octogenarians</title><title>Journal of the American Geriatrics Society</title><addtitle>J Am Geriatr Soc</addtitle><description>OBJECTIVES: To study the safety and benefit of mitral balloon valvotomy (MBV) in patients aged ≥ 80 years. SETTING: A tertiary cardiac centre DESIGN: A retrospective study of 20 octogenarians (mean age 83, range 80–89 years) in whom percutaneous MBV was performed as a definitive or palliative treatment for severe mitral stenosis. All were in New York Heart Association (NYHA) symptom class III or IV. Fourteen had been judged unfit for cardiac surgery. Hemodynamic data was recorded before and after MBV. Symptomatic outcome was documented at 1 month for all patients. Outcome at 1 year was available for 16 patients. RESULTS: Dilatation of the mitral valve was achieved in all patients without major complications. Mean mitral valve area increased 106% from 0.81 (± 0.3) to 1.67 (± 0.8) cm2, transvalvular gradient decreased from 11.8 (± 4.8) to 5.6 (± 2.9) mm Hg, cardiac output increased from 3.1 (± 0.6) to 4.1 (± 1.4) 1/min (all P &lt; .01). Eight of these 20 patients obtained a valve area ≥ 1.5 cm2, and 16 obtained an area ≥ 1.2 cm2. One month after BMV, all patients were alive, and 16 of the 20 patients were improved by at least one NYHA class. This improvement was sustained in 7 of 16 patients followed up for 1 year. More severe mitral valve degenerative change, determined by echocardiography, was associated with poorer outcome. CONCLUSIONS: In this group of very old and frail patients, MBV was safe and resulted in significant immediate improvement. Sustained symptomatic benefit at 1 year was obtained in those with less extensive leaflet and subvalvular disease. 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Vascular system</subject><subject>Cardiovascular disease</subject><subject>Catheterization - adverse effects</subject><subject>Catheterization - methods</subject><subject>Comorbidity</subject><subject>Echocardiography</subject><subject>Endocardial and cardiac valvular diseases</subject><subject>Female</subject><subject>Frail Elderly</subject><subject>Geriatric Assessment</subject><subject>Geriatrics</subject><subject>Heart</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>mitral balloon valvotomy</subject><subject>mitral stenosis</subject><subject>Mitral Valve Stenosis - classification</subject><subject>Mitral Valve Stenosis - diagnostic imaging</subject><subject>Mitral Valve Stenosis - physiopathology</subject><subject>Mitral Valve Stenosis - therapy</subject><subject>octogenarian</subject><subject>Older people</subject><subject>Patient Selection</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><issn>0002-8614</issn><issn>1532-5415</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkE1v1DAQhi0EotvCX0BWhbgljO3EdrigUsGWqh-HFnq0nMSBLIldbG_Z_fc4SlQQN-ZiS_PM6_GD0DGBnKR6u8lJyWhWFqTMKQDksQYuK5HvnqDVY-spWqUezSQnxQE6DGEDQChI-RwdEKi4ZFCs0NVlH70e8Ac9DM5Z_FUPDy66cY8753H8bvCtNzqOxkbsOrzQN9FYF_qAe4uvm-i-Gat9r214gZ51egjm5XIeoS-fPt6enmUX1-vPpycXWVPwUmRt3VbCaM6MZrwC4FoUsoK6M5yXEjpTCSYK0tUdE9BCKxrKGqhKSkxFJa3ZEXoz595793NrQlRjHxozDNoatw1K0FTARAKP_wE3butt2k1RkoBkSybo3Qw13oXgTafufT9qv1cE1KRcbdTkVU1e1aRcLcrVLg2_Wl7Y1qNp_xqdHSfg9QLo0Oih89o2ffjDlQTS1xL2fsZ-9YPZ_8cG6nx9M91SQjYn9CGa3WOC9j8UTz5LdXe1VnfV-oyyc6Yu2W_lP6uF</recordid><startdate>200008</startdate><enddate>200008</enddate><creator>Sutaria, Nilesh</creator><creator>Elder, Andrew T.</creator><creator>Shaw, Thomas R. 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Vascular system</topic><topic>Cardiovascular disease</topic><topic>Catheterization - adverse effects</topic><topic>Catheterization - methods</topic><topic>Comorbidity</topic><topic>Echocardiography</topic><topic>Endocardial and cardiac valvular diseases</topic><topic>Female</topic><topic>Frail Elderly</topic><topic>Geriatric Assessment</topic><topic>Geriatrics</topic><topic>Heart</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>mitral balloon valvotomy</topic><topic>mitral stenosis</topic><topic>Mitral Valve Stenosis - classification</topic><topic>Mitral Valve Stenosis - diagnostic imaging</topic><topic>Mitral Valve Stenosis - physiopathology</topic><topic>Mitral Valve Stenosis - therapy</topic><topic>octogenarian</topic><topic>Older people</topic><topic>Patient Selection</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sutaria, Nilesh</creatorcontrib><creatorcontrib>Elder, Andrew T.</creatorcontrib><creatorcontrib>Shaw, Thomas R. 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D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mitral Balloon Valvotomy for the Treatment of Mitral Stenosis in Octogenarians</atitle><jtitle>Journal of the American Geriatrics Society</jtitle><addtitle>J Am Geriatr Soc</addtitle><date>2000-08</date><risdate>2000</risdate><volume>48</volume><issue>8</issue><spage>971</spage><epage>974</epage><pages>971-974</pages><issn>0002-8614</issn><eissn>1532-5415</eissn><coden>JAGSAF</coden><abstract>OBJECTIVES: To study the safety and benefit of mitral balloon valvotomy (MBV) in patients aged ≥ 80 years. SETTING: A tertiary cardiac centre DESIGN: A retrospective study of 20 octogenarians (mean age 83, range 80–89 years) in whom percutaneous MBV was performed as a definitive or palliative treatment for severe mitral stenosis. All were in New York Heart Association (NYHA) symptom class III or IV. Fourteen had been judged unfit for cardiac surgery. Hemodynamic data was recorded before and after MBV. Symptomatic outcome was documented at 1 month for all patients. Outcome at 1 year was available for 16 patients. RESULTS: Dilatation of the mitral valve was achieved in all patients without major complications. Mean mitral valve area increased 106% from 0.81 (± 0.3) to 1.67 (± 0.8) cm2, transvalvular gradient decreased from 11.8 (± 4.8) to 5.6 (± 2.9) mm Hg, cardiac output increased from 3.1 (± 0.6) to 4.1 (± 1.4) 1/min (all P &lt; .01). Eight of these 20 patients obtained a valve area ≥ 1.5 cm2, and 16 obtained an area ≥ 1.2 cm2. One month after BMV, all patients were alive, and 16 of the 20 patients were improved by at least one NYHA class. This improvement was sustained in 7 of 16 patients followed up for 1 year. More severe mitral valve degenerative change, determined by echocardiography, was associated with poorer outcome. CONCLUSIONS: In this group of very old and frail patients, MBV was safe and resulted in significant immediate improvement. Sustained symptomatic benefit at 1 year was obtained in those with less extensive leaflet and subvalvular disease. In patients with severe degenerative valve disease on echocardiography, but unacceptable surgical risk, MBV offers short‐term palliation. J Am Geriatr Soc 48:971–974, 2000.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>10968304</pmid><doi>10.1111/j.1532-5415.2000.tb06897.x</doi><tpages>4</tpages></addata></record>
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subjects Activities of Daily Living
Aged
Aged, 80 and over
Biological and medical sciences
Cardiology. Vascular system
Cardiovascular disease
Catheterization - adverse effects
Catheterization - methods
Comorbidity
Echocardiography
Endocardial and cardiac valvular diseases
Female
Frail Elderly
Geriatric Assessment
Geriatrics
Heart
Hemodynamics
Humans
Male
Medical sciences
mitral balloon valvotomy
mitral stenosis
Mitral Valve Stenosis - classification
Mitral Valve Stenosis - diagnostic imaging
Mitral Valve Stenosis - physiopathology
Mitral Valve Stenosis - therapy
octogenarian
Older people
Patient Selection
Predictive Value of Tests
Prognosis
Retrospective Studies
Severity of Illness Index
Surgery
Treatment Outcome
title Mitral Balloon Valvotomy for the Treatment of Mitral Stenosis in Octogenarians
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