Role of adenosine and P2 receptors in the penile tumescence in anesthetized dogs

We studied the role of adenosine and P2 receptors in the pelvic nerve stimulation-induced penile tumescence in anesthetized dogs. A local intracavernous injection of adenosine induced the tumescence, which was abolished by intracavernous 8-( p-sulfophenyl)theophylline (8-SPT), an unspecific adenosin...

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Veröffentlicht in:	European journal of pharmacology 2001-08, Vol.425 (1), p.51-55
Hauptverfasser:	Noto, Tsunehisa, Inoue, Hirotaka, Mochida, Hideki, Kikkawa, Kohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - pharmacology Adenosine Diphosphate - analogs & derivatives Adenosine Diphosphate - pharmacology Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Anesthesia Animals ATP Biological and medical sciences Dogs Dose-Response Relationship, Drug Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Injections, Intravenous Male Mammalian male genital system Morphology. Physiology NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Pelvic nerve Penile Erection - drug effects Penis - drug effects Penis - innervation Penis - physiology Purinergic P2 Receptor Agonists Purinergic P2 Receptor Antagonists Receptors, Purinergic P2 - physiology T-1032 Theophylline - analogs & derivatives Theophylline - pharmacology Thionucleotides - pharmacology Triazines - pharmacology Triazoles - pharmacology Vertebrates: reproduction
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