The coming impact of gene expression profiling on the diagnosis and treatment of HCV-associated liver disease
Gene expression profiling allows the level of activity of thousands of genes to be monitored simultaneously. Profiling is often carried out on specialized chips or slides, which have microarrays of gene targets at predetermined addresses. In the immediate future, microarrays promise to yield new ins...
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| Veröffentlicht in: | Antiviral research 2001-11, Vol.52 (2), p.173-179 |
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| container_end_page | 179 |
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| container_title | Antiviral research |
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| creator | Branch, Andrea D. Walewski, José L. |
| description | Gene expression profiling allows the level of activity of thousands of genes to be monitored simultaneously. Profiling is often carried out on specialized chips or slides, which have microarrays of gene targets at predetermined addresses. In the immediate future, microarrays promise to yield new insights into hepatitis C virus (HCV) pathogenesis and to produce ‘signatures’ that can be used in molecular diagnostics. In the longer-term, they may aid the development of serological tests by identifying genes encoding secretory proteins produced by HCV-infected livers, and they may suggest new avenues for disease intervention by detecting genes whose products are retained in the infected liver. |
| doi_str_mv | 10.1016/S0166-3542(01)00182-6 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0166-3542 |
| ispartof | Antiviral research, 2001-11, Vol.52 (2), p.173-179 |
| issn | 0166-3542 1872-9096 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72220347 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Gene Expression Profiling Hepatitis C - diagnosis Hepatitis C - genetics Hepatitis C - therapy Hepatitis C - virology Hepatitis C virus Human viral diseases Humans Infectious diseases Liver - metabolism Medical sciences Messenger RNAs Oligonucleotide Array Sequence Analysis Viral diseases Viral hepatitis |
| title | The coming impact of gene expression profiling on the diagnosis and treatment of HCV-associated liver disease |
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