Down‐regulated melanoma differentiation associated gene (mda‐7) expression in human melanomas

The melanoma differentiation associated gene‐7 (mda‐7) has a potential inhibitory role in melanoma progression, although the mechanisms underlying this effect are still unknown. mda‐7 mRNA has been found to be present at higher levels in cultured normal melanocytes compared with metastatic melanoma...

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Veröffentlicht in:	International journal of cancer 2001-10, Vol.94 (1), p.54-59
Hauptverfasser:	Ekmekcioglu, Suhendan, Ellerhorst, Julie, Mhashilkar, Abner M., Sahin, Aysegul A., Read, Christine M., Prieto, Victor G., Chada, Sunil, Grimm, Elizabeth A.
Format:	Artikel
Sprache:	eng
Schlagworte:	adenovirus Apoptosis Biological and medical sciences Cell Differentiation Cell Division Cytoplasm - chemistry Dermatology Down-Regulation G2 Phase Gene Expression Regulation, Neoplastic gene therapy Genes, Tumor Suppressor Growth Substances - analysis Growth Substances - genetics Growth Substances - physiology Humans Interleukins mda‐7 Medical sciences Melanocytes - chemistry Melanoma - metabolism Melanoma - pathology Melanoma - secondary melanoma development Mitosis Tumor Cells, Cultured tumor suppressor genes Tumors of the skin and soft tissue. Premalignant lesions
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