P-selectin participates in cardiopulmonary bypass–induced inflammatory response in association with nitric oxide and peroxynitrite production

Objectives: P-selectin participates in the development of inflammatory disorders. Cardiopulmonary bypass is thought to induce inflammatory response and increase nitric oxide production. To evaluate the role of P-selectin in bypass-induced inflammatory response and its association with nitric oxide p...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2000-09, Vol.120 (3), p.558-565
Hauptverfasser:	Hayashi, Yoshitaka, Sawa, Yoshiki, Nishimura, Motonobu, Tojo, Shinichiro J., Fukuyama, Naoto, Nakazawa, Hiroe, Matsuda, Hikaru
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia depending on type of surgery Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antibodies, Monoclonal Biological and medical sciences Cardiopulmonary Bypass - adverse effects Inflammation - blood Inflammation - etiology Interleukin-6 - blood Male Medical sciences Nitrates - blood Nitric Oxide - biosynthesis Nitrites - analysis Nitrites - blood P-Selectin - immunology P-Selectin - physiology Rats Rats, Sprague-Dawley Thoracic and cardiovascular surgery. Cardiopulmonary bypass Tyrosine - analogs & derivatives Tyrosine - blood
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