Alterations of Fas (APO-1/CD 95) gene and its relationship with p53 in non small cell lung cancer

The Fas (APO-1/CD95) system regulates a number of physiological and pathological processes of cell death. The ligand for Fas induces apoptosis by interacting with a transmembrane cell surface Fas receptor. The key role of the Fas system has been studied mostly in the immune system, but Fas mutations...

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Veröffentlicht in:	Oncogene 2001-10, Vol.20 (45), p.6632-6637
Hauptverfasser:	BOLDRINI, Laura, FAVIANA, Pinuccia, SIMI, Paolo, BASOLO, Fulvio, FONTANINI, Gabriella, PISTOLESI, Francesca, GISFREDI, Silvia, DI QUIRICO, Dagmar, LUCCHI, Marco, MUSSI, Alfredo, ANGELETTI, Carlo Alberto, BALDINOTTI, Fulvia, FOGLI, Antonella
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Autocrine signalling Biological and medical sciences Cancer Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology CD95 antigen Cell death Cell physiology Cell surface Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Conformation DNA sequencing Fas antige Fas antigen fas Receptor - biosynthesis fas Receptor - genetics Fundamental and applied biological sciences. Psychology Gene expression Gene polymorphism Genes, p53 Genetic aspects Genetic research Humans Immune system Ligands Lung - metabolism Lung cancer Lung cancer, Non-small cell Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Messenger RNA Molecular and cellular biology Mutation Non-small cell lung carcinoma p53 Protein Polymerase chain reaction Polymorphism, Single-Stranded Conformational Promoter Regions, Genetic Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis RNA, Neoplasm - biosynthesis Small cell lung carcinoma Tumor Cells, Cultured Tumor proteins Tumor Suppressor Protein p53 - biosynthesis Tumor Suppressor Protein p53 - genetics Tumors
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