A solid-phase synthetic strategy for the preparation of peptide-based affinity labels: synthesis of dynorphin A analogs

: Solid‐phase synthetic methodology was developed for the preparation of peptide‐based affinity labels. The initial peptides synthesized were dynorphin A (Dyn A) analogs [Phe(p‐X)4,d‐Pro10]Dyn A(1–11)NH2 containing isothiocyanate (X = –N=C=S) and bromoacetamide (X = –NHCOCH2Br) groups. The peptides...

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Veröffentlicht in:	The journal of peptide research 2000-08, Vol.56 (2), p.80-87
Hauptverfasser:	Leelasvatanakij, L., Aldrich, J.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	allyloxycarbonyl (Alloc) Amino Acid Sequence Chromatography, High Pressure Liquid dynorphin analogs Dynorphins - chemical synthesis Dynorphins - chemistry opioid peptide analogs orthogonal protection strategy Spectrometry, Mass, Fast Atom Bombardment
Online-Zugang:	Volltext
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