Sensitivity of FISH in detection of MLL translocations

Fluorescence in situ hybridisation (FISH) detection of MLL translocations is now commonplace in cytogenetics laboratories. One of the most widely used probes is the Oncor MLL probe (Oncor, Gaithersburg, MD) that theoretically demonstrates the presence of an MLL rearrangement by a splitting of the FI...

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Veröffentlicht in:	Genes chromosomes & cancer 2000-10, Vol.29 (2), p.180-185
Hauptverfasser:	Cuthbert, Gavin, Thompson, Karen, Breese, Gareth, McCullough, Simon, Bown, Nick
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Southern DNA Probes - genetics Female Fluorescent Dyes Genetic Variation - genetics GTP Phosphohydrolases GTP-Binding Proteins - analysis GTP-Binding Proteins - genetics Humans In Situ Hybridization, Fluorescence - methods Sensitivity and Specificity Septins Sequence Deletion - genetics Translocation, Genetic - genetics
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