Expression patterns of the erbB subfamily mRNA in canine benign and malignant mammary tumors

ErbB subfamily genes, known as proto-oncogenes, encode receptor tyrosine kinases, and are expressed in relation to tumorigenesis of the mammary gland in humans. In this study, we examined the expression of erbB subfamily mRNAs in two canine normal mammary glands and 12 mammary tumor samples by rever...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2001, Vol.63(9), pp.949-954
Hauptverfasser:	Matsuyama, S. (Osaka Prefectural Univ., Sakai (Japan)), Nakamura, M, Yonezawa, K, Shimada, T, Ohashi, F, Takamori, Y, Kubo, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence canine Dog Diseases - genetics Dog Diseases - metabolism DOGS erbB subfamily Female GENE EXPRESSION Gene Expression Regulation, Neoplastic - genetics Genes, erbB - genetics MAMMARY GLANDS Mammary Neoplasms, Animal - genetics Mammary Neoplasms, Animal - metabolism mammary tumor MESSENGER RNA Molecular Sequence Data NEOPLASMS Oncogene Proteins v-erbB - biosynthesis Oncogene Proteins v-erbB - genetics Reverse Transcriptase Polymerase Chain Reaction - veterinary RNA, Messenger - genetics RNA, Messenger - metabolism RT-PCR Sequence Homology, Nucleic Acid tumor marker
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