Involvement of Phosphorylation of Myosin Phosphatase by ROCK in Trabecular Meshwork and Ciliary Muscle Contraction

The control of smooth muscle contraction is an important factor in maintaining normal intraoculer pressure. However, the specific factors causing changes in control by phosphorylation/dephosphorylation schemes in the eye are not well-defined. The purposes of this experiment were to (i) determine the...

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Veröffentlicht in:	Biochemical and biophysical research communications 2001-10, Vol.288 (2), p.296-300
Hauptverfasser:	Fukiage, Chiho, Mizutani, Kanako, Kawamoto, Yoko, Azuma, Mitsuyoshi, Shearer, Thomas R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ciliary muscle contraction, trabecular meshwork contraction Intracellular Signaling Peptides and Proteins Macaca fascicularis Male Muscle Contraction - physiology Muscle, Smooth - physiology myosin phosphatase Myosin-Light-Chain Phosphatase Phosphoprotein Phosphatases - metabolism Phosphorylation Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Rabbits rho-Associated Kinases Rho-associated protein kinase RNA, Messenger - metabolism Spasm - enzymology Spasm - metabolism Trabecular Meshwork - enzymology Trabecular Meshwork - metabolism
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