Annexin 1 peptides protect against experimental myocardial ischemia‐reperfusion: analysis of their mechanism of action

Myocardial reperfusion injury is associated with the infiltration of blood‐borne polymorphonuclear leukocytes. We have previous described the protection afforded by annexin 1 (ANXA1) in an experimental model of rat myocardial ischemia‐reperfu‐sion (IR) injury. We examined the 1) amino acid region of...

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Veröffentlicht in:	The FASEB journal 2001-10, Vol.15 (12), p.2247-2256
Hauptverfasser:	La, Mylinh, D'Amico, Michele, Bandiera, Silvio, Filippo, Clara Di, Oliani, Sonia M., Gavins, Felicity N. E., Flower, Roderick J., Perretti, Mauro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annexin A1 - chemistry Annexin A1 - metabolism Annexin A1 - pharmacology Chemotaxis, Leukocyte fMLP FPR Hemodynamics - drug effects Interleukin-1 - metabolism Kinetics lipocortin 1 Myocardial Reperfusion Injury - metabolism Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - prevention & control Myocardium - metabolism neutrophil Neutrophils - immunology Oligopeptides - pharmacology Peptides - pharmacology Peroxidase - metabolism Rats receptor Receptors, Formyl Peptide Receptors, Immunologic - antagonists & inhibitors Receptors, Immunologic - physiology Receptors, Peptide - antagonists & inhibitors Receptors, Peptide - physiology
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