Up-regulation of S100C in normal human fibroblasts in the process of aging in vitro

S100 proteins belonging to the EF-hand Ca 2+-binding protein family regulate a variety of cellular processes via interaction with different target proteins. Several diseases, including cancer and Alzheimer's disease, are related to a disorder of multifunctional S100 proteins, which are expresse...

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Veröffentlicht in:	Experimental gerontology 2001-08, Vol.36 (8), p.1317-1325
Hauptverfasser:	Sakaguchi, Masakiyo, Miyazaki, Masahiro, Kondo, Tadashi, Namba, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Division Cell Line Cell Nucleus - metabolism Cellular Senescence - genetics Cellular Senescence - physiology Cyclin-Dependent Kinase Inhibitor p21 Cyclins - genetics Cyclins - metabolism Fibroblasts - cytology Fibroblasts - metabolism Growth arrest Human senescent fibroblasts Humans In Vitro Techniques S100 Proteins - genetics S100 Proteins - metabolism S100C Up-Regulation
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