Interstitial cystitis: urgency and frequency syndrome

Interstitial cystitis is a chronic, severely debilitating disease of the urinary bladder. Excessive urgency and frequency of urination, suprapubic pain, dyspareunia, chronic pelvic pain and negative urine cultures are characteristic of interstitial cystitis. The course of the disease is usually mark...

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Veröffentlicht in:American family physician 2001-10, Vol.64 (7), p.1199-1206
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description Interstitial cystitis is a chronic, severely debilitating disease of the urinary bladder. Excessive urgency and frequency of urination, suprapubic pain, dyspareunia, chronic pelvic pain and negative urine cultures are characteristic of interstitial cystitis. The course of the disease is usually marked by flare-ups and remissions. Other conditions that should be ruled out include bacterial cystitis, urethritis, neoplasia, vaginitis and vulvar vestibulitis. Interstitial cystitis is diagnosed by cystoscopy and hydrodistention of the bladder. Glomerulations or Hunner's ulcers found at cystoscopy are diagnostic. Oral treatments of interstitial cystitis include pentosan polysulfate, tricyclic antidepressants and antihistamines. Intravesicular therapies include hydrodistention, dimethyl sulfoxide and heparin, or a combination of agents. Referral to a support group should be offered to all patients with interstitial cystitis.
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source MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Administration, Intravesical
Administration, Oral
Analgesics, Non-Narcotic - administration & dosage
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Anticoagulants - administration & dosage
Antidepressive Agents, Tricyclic - administration & dosage
Cystitis, Interstitial - complications
Cystitis, Interstitial - diagnosis
Cystitis, Interstitial - drug therapy
Cystitis, Interstitial - pathology
Cystitis, Interstitial - therapy
Cystoscopy
Decision Trees
Diagnosis, Differential
Dimethyl Sulfoxide - administration & dosage
Drug Therapy, Combination
Excretory system
Health care
Heparin - administration & dosage
Histamine H1 Antagonists - administration & dosage
Humans
Medical disorders
Pentosan Sulfuric Polyester - administration & dosage
Recurrence
Urine
title Interstitial cystitis: urgency and frequency syndrome
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