Low prevalence of GAD and IA2 antibodies in schoolchildren from a village in the southwestern section of The Netherlands

Glutamic acid decarboxylase (GAD) and insulinoma antigen 2 (IA2) antibodies are increasingly used as a tool to predict type I diabetes in children and as a differential diagnostic tool to distinguish type I and type II diabetes in adults. However, the background frequency of these antibodies in the...

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Veröffentlicht in:	Human immunology 2001-10, Vol.62 (10), p.1106-1110
Hauptverfasser:	Batstra, M.R, Petersen, J.S, Bruining, G.J, Grobbee, D.E, de Man, S.A, Molenaar, J.L, Dyrberg, T, Aanstoot, H.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantibodies - blood Autoantigens Child Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 1 - immunology Female Follow-Up Studies GAD antibodies Glutamate Decarboxylase - immunology Humans IA-2 antigen IA2 antibodies insulinoma Male Membrane Proteins - immunology Netherlands - epidemiology Predictive Value of Tests Protein Tyrosine Phosphatase, Non-Receptor Type 1 Protein Tyrosine Phosphatases - immunology Receptor-Like Protein Tyrosine Phosphatases, Class 8 schoolchildren screening Seroepidemiologic Studies type I diabetes
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