Regulation of Phenobarbital-Mediated Induction of CYP102 (Cytochrome P450BM-3) in Bacillus megaterium by Phytochemicals from Soy and Green Tea

Cytochrome P450 102 (CYP102 or Cytochrome P450BM - 3) is induced in Bacillus megaterium by barbiturates, perioxisome proliferators, estrogen, and nonsteroidal antiinflammatory drugs. We have previously demonstrated that a CYP102 construct (BMC 143) coupled with a luciferase reporter gene can be used...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2001-10, Vol.49 (10), p.4930-4936
Hauptverfasser:	Rajnarayanan, Rajendram V, Rowley, Christopher W, Hopkins, Nancy E, Alworth, William L
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus megaterium - enzymology Bacterial Proteins Bacteriology Biological and medical sciences Catechin - pharmacology Chromans - pharmacology Coumestrol - pharmacology Cytochrome P-450 Enzyme System - biosynthesis Equol Fundamental and applied biological sciences. Psychology Genetics Genistein - pharmacology Glycine max - chemistry Isoflavones - pharmacology Microbiology Mixed Function Oxygenases - biosynthesis NADPH-Ferrihemoprotein Reductase Phenobarbital - pharmacology Tea - chemistry Zearalenone - pharmacology
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