Successful treatment of solar urticaria by extracorporeal photochemotherapy (photopheresis) - a case report
: Solar urticaria is characterized by erythema and whealing immediately after exposure to ultraviolet radiation and/or visible light. We report about a patient with severe solar urticaria, who was highly sensitive to both UVA radiation and visible light with a Minimal Urticaria Dose (MUD) of 7 J/cm2...
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Veröffentlicht in: | Photodermatology, photoimmunology & photomedicine photoimmunology & photomedicine, 2002-08, Vol.18 (4), p.196-198 |
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creator | Mang, R. Stege, H. Budde, M.-A. Ruzicka, T. Krutmann, J. |
description | : Solar urticaria is characterized by erythema and whealing immediately after exposure to ultraviolet radiation and/or visible light. We report about a patient with severe solar urticaria, who was highly sensitive to both UVA radiation and visible light with a Minimal Urticaria Dose (MUD) of 7 J/cm2 UVA. Management of this patient was extremely difficult because standard treatment with oral antihistamines, hardening with UVA, UVB, visible light or oral PUVA and even oral cyclosporin A were completely ineffective. We therefore decided to perform extracorporeal photochemotherapy (photopheresis, ECP). After nine treatment cycles with photopheresis the MUD increased from 7 J/cm2 UVA before treatment to 22 J/cm2 UVA. This hardening effect was associated with a significant decrease of the frequency and severity of whealing and the accompanying symptoms (pain, fatigue, pruritus).
Conclusion: Photopheresis might be of some benefit in selected patients with otherwise intractable solar urticaria. |
doi_str_mv | 10.1034/j.1600-0781.2002.00683.x |
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Conclusion: Photopheresis might be of some benefit in selected patients with otherwise intractable solar urticaria.</description><subject>Biological and medical sciences</subject><subject>Diseases of the skin. Cosmetics</subject><subject>extracorporeal photopheresis</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Photopheresis</subject><subject>Photosensitivity Disorders - drug therapy</subject><subject>Photosensitivity Disorders - pathology</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Skin - pathology</subject><subject>solar urticaria</subject><subject>Urticaria - drug therapy</subject><subject>Urticaria - etiology</subject><subject>Urticaria - pathology</subject><issn>0905-4383</issn><issn>1600-0781</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1v0zAUhi0EYt3gLyDfgOAi4Th27PgGCVWwgSao-BCIG8t1TtR0SR1sR2v_Pclabbdc-et532M9hFAGOQMu3m5zJgEyUBXLC4AiB5AVz_ePyOL-4TFZgIYyE7ziZ-Q8xi0ACAHsKTljBdcgVbkgN99H5zDGZuxoCmhTj7tEfUOj72ygY0its6G1dH2guE_BOh8GP4EdHTY-ebfB3qcNBjsc6Ou7q2E6YWzjG5pRS52NSANOmfSMPGlsF_H5ab0gPz9--LG8yq6_Xn5avr_OnOCCZ7oUStVCIIjalugaLa2qNOOSsxpq3ayVBF26mjVWOs2cZAVjJXeg1opVDb8gr469Q_B_R4zJ9G102HV2h36MRhVMK6blBFZH0AUfY8DGDKHtbTgYBmYWbbZm9mlmn2YWbe5Em_0UfXGaMa57rB-CJ7MT8PIE2Ohs1wS7c2184HhVcYBq4t4dudu2w8N_f8CsrlareTsVZMeCNibc3xfYcGOk4qo0v75cmm-f-VLJ30vzh_8DwD2pnQ</recordid><startdate>200208</startdate><enddate>200208</enddate><creator>Mang, R.</creator><creator>Stege, H.</creator><creator>Budde, M.-A.</creator><creator>Ruzicka, T.</creator><creator>Krutmann, J.</creator><general>Blackwell Science, Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200208</creationdate><title>Successful treatment of solar urticaria by extracorporeal photochemotherapy (photopheresis) - a case report</title><author>Mang, R. ; Stege, H. ; Budde, M.-A. ; Ruzicka, T. ; Krutmann, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4343-95477d44e04da5ecf96a78913631d0d9fb76095cd1fa6c91c6121153c07b718f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biological and medical sciences</topic><topic>Diseases of the skin. Cosmetics</topic><topic>extracorporeal photopheresis</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Photopheresis</topic><topic>Photosensitivity Disorders - drug therapy</topic><topic>Photosensitivity Disorders - pathology</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Skin - pathology</topic><topic>solar urticaria</topic><topic>Urticaria - drug therapy</topic><topic>Urticaria - etiology</topic><topic>Urticaria - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mang, R.</creatorcontrib><creatorcontrib>Stege, H.</creatorcontrib><creatorcontrib>Budde, M.-A.</creatorcontrib><creatorcontrib>Ruzicka, T.</creatorcontrib><creatorcontrib>Krutmann, J.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Photodermatology, photoimmunology & photomedicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mang, R.</au><au>Stege, H.</au><au>Budde, M.-A.</au><au>Ruzicka, T.</au><au>Krutmann, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Successful treatment of solar urticaria by extracorporeal photochemotherapy (photopheresis) - a case report</atitle><jtitle>Photodermatology, photoimmunology & photomedicine</jtitle><addtitle>Photodermatol Photoimmunol Photomed</addtitle><date>2002-08</date><risdate>2002</risdate><volume>18</volume><issue>4</issue><spage>196</spage><epage>198</epage><pages>196-198</pages><issn>0905-4383</issn><eissn>1600-0781</eissn><abstract>: Solar urticaria is characterized by erythema and whealing immediately after exposure to ultraviolet radiation and/or visible light. We report about a patient with severe solar urticaria, who was highly sensitive to both UVA radiation and visible light with a Minimal Urticaria Dose (MUD) of 7 J/cm2 UVA. Management of this patient was extremely difficult because standard treatment with oral antihistamines, hardening with UVA, UVB, visible light or oral PUVA and even oral cyclosporin A were completely ineffective. We therefore decided to perform extracorporeal photochemotherapy (photopheresis, ECP). After nine treatment cycles with photopheresis the MUD increased from 7 J/cm2 UVA before treatment to 22 J/cm2 UVA. This hardening effect was associated with a significant decrease of the frequency and severity of whealing and the accompanying symptoms (pain, fatigue, pruritus).
Conclusion: Photopheresis might be of some benefit in selected patients with otherwise intractable solar urticaria.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science, Ltd</pub><pmid>12390675</pmid><doi>10.1034/j.1600-0781.2002.00683.x</doi><tpages>3</tpages></addata></record> |
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subjects | Biological and medical sciences Diseases of the skin. Cosmetics extracorporeal photopheresis Humans Male Medical sciences Middle Aged Photopheresis Photosensitivity Disorders - drug therapy Photosensitivity Disorders - pathology Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Skin - pathology solar urticaria Urticaria - drug therapy Urticaria - etiology Urticaria - pathology |
title | Successful treatment of solar urticaria by extracorporeal photochemotherapy (photopheresis) - a case report |
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