Serum and lower respiratory tract drug concentrations after tobramycin inhalation in young children with cystic fibrosis

Objectives: To assess the serum and lower respiratory tract tobramycin concentrations (CT) produced by a single dose of tobramycin for inhalation delivered by a nebulizer and a compressor in patients with cystic fibrosis (CF) 6 months to 6 years of age. Study design: We performed a dose escalation s...

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