Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist

2-Chloro-N(6)-methyl-(N )-methanocarba-2'-deoxyadenosine-3',5'- bisphosphate (MRS2279) was developed previously as a selective high-affinity, non-nucleotide P2Y(1) receptor (P2Y1-R) antagonist (J Med Chem 43:829-842, 2002; Br J Pharmacol 135:2004-2010, 2002). We have taken advantage o...

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Veröffentlicht in:	Molecular pharmacology 2002-11, Vol.62 (5), p.1249-1257
Hauptverfasser:	Waldo, Gary L, Corbitt, James, Boyer, José L, Ravi, Gnana, Kim, Hak Sung, Ji, Xiao-Duo, Lacy, James, Jacobson, Kenneth A, Harden, T Kendall
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - analogs & derivatives Adenosine Diphosphate - chemical synthesis Adenosine Diphosphate - chemistry Adenosine Diphosphate - pharmacology Animals Cells, Cultured Female Humans Insecta - cytology Purinergic P2 Receptor Antagonists Radiopharmaceuticals - chemical synthesis Radiopharmaceuticals - chemistry Radiopharmaceuticals - pharmacology Rats Rats, Sprague-Dawley Receptors, Purinergic P2 - analysis Receptors, Purinergic P2Y1 Tritium
Online-Zugang:	Volltext
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