Regulation of expression and activity of four PKC isozymes in confluent and mechanically stimulated UMR-108 osteoblastic cells

The transcript (mRNA), protein levels, enzyme activity, and cellular localization of four protein kinase C (PKC) isozymes identified in rat osteogenic sarcoma cells (UMR‐108) were studied at confluent density and during mechanical stress (cyclic stretch). Western blot analysis indicated that growth...

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Veröffentlicht in:	Journal of cellular physiology 2001-11, Vol.189 (2), p.216-228
Hauptverfasser:	Geng, W.D., Boskovic, G., Fultz, M.E., Li, C., Niles, R.M., Ohno, S., Wright, G.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - ultrastructure Animals Cell Culture Techniques - methods Cell Size Isoenzymes - biosynthesis Isoenzymes - genetics Isoenzymes - metabolism Microscopy, Confocal Osteoblasts - cytology Osteoblasts - enzymology Osteoblasts - ultrastructure Protein Kinase C - biosynthesis Protein Kinase C - genetics Protein Kinase C - metabolism Protein Kinase C-alpha Protein Kinase C-delta Protein Kinase C-epsilon Rats RNA, Messenger - biosynthesis Stress, Mechanical Transcription, Genetic Tumor Cells, Cultured
Online-Zugang:	Volltext
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